Aseptic Filling and Closing Machines

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Aseptic Filling and Closing Machines [25]

BAUSCH+STRÖBEL Liquid Filling and Closing Machines BAUSCH+STRÖBEL FFV6010
Liquid Filling and Closing Machines BAUSCH+STRÖBEL FFV6010
22C16
BAUSCH+STRÖBEL
FFV6010
2005

Filling and closing machine designed for the simultaneaous processing of 6 vials or oter small stable bottles of glass or plastic.


Working Sequence
-Feeding of the vials into the machine by a machine upstream or by manual bulk loading into a rotary table, an RPE BI-FLOW conveyor or an infeed belt with a feed screw.
- Separation of the vials by an infeed star wheel and transfer to the transport star wheel
- Dosing filling
- Closing with rubber stopper dropper insertion etc…
Discharge star wheel with transfer to the following machine or magazine loading unit .

Dosing :
The dosing station is equipped with with 6 valveless rotary piston pumps .
Thes pumps are made of two parts only and are hight-quality precision tolls which guarantee excellent dosing precision.
They are easy to remove , clean and sterilize – as are all the parts which are in contact with the product.
Depending on the product to be dispensed, the pumps may be made of stainless steel, glass or ceramics.
The CIP SIP version of the dosing units ( cleaning in place – sterilizing in place ) permits the cleaning and sterilizing of the entire dosing system without dismantling and assembly.
The central dose adjustment and the individual fine adjustment for eache pum are done by micrometer screws.
A photo cell at the infeed checks each transport pocket for the presence of a vial and controls the dosing pumps and the closing tools according to the principle “ no bottle – no filling – no closure”.

Closing:
Sorting bowls and vibratory tracks feed the stoppers, dropper inserts, etc… automatically and with low particle generation . The insertion tolls pick up the stoppers by vacuum and set them precisely in the bottle opening.
All the parts in contact with the stoppers are easy to clean ad sterilize.
They can be removed and assembled effortlessly .

Size change
Resetting the machine for a different container or closure size even under clean room conditions, is simple and quick due to :
- The exchange of complete size parts
- - finely adjustable height setting

Year of construction : 1987 3.5 kw - 50 hz - 24 v - 220/380 1780 kg

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ROMACO
22F121
ROMACO
Macofar Tipo MT8
2008

22F120 (MAtr.14/08 )
2 Microdosing machine MACOFAR ROMACO MT/8 (2008)
Technical details:
• Production speed
• (according to the product) Up to 8000 vials per hour
• Working Diameter From 15 up to 50 mm with the relative format
• Working height From 35 up to 110 mm
• Dosing range From 50 up to 3600 mg (according to the dosing disk)
• Electrical details 220V - 380 V Trifasico+N 50/60 Hz (with auto converter)
• Power installed 1,3 Kw
• Air compress consumption 35 Nm3/h
• Net weight 1600 Kg.

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Romaco Macofar Aseptic Filling and Closing Machines Romaco Macofar MT4
Aseptic Filling and Closing Machines Romaco Macofar MT4
22F123
Romaco Macofar
MT4
2008

22F123 (MAtr.16/08 )

CAPPING MACOFAR ROMACO MT4 (2008)

TECHNICAL DETAILS

• Production speed Up to 8000 vials per hour (Mechanical speed depend on the product)

• Vials diameter 15 up to 50 mm

• Vials height From 35 up to 110 mm

• Electrical details 220V - 380 V Trifasico+N 50/60 Hz (Auto converter)

• Power installed 2,5 Kw

• Net weight 800 Kg.

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IMA Aseptic Filling and Closing Machines IMA F2000
Aseptic Filling and Closing Machines IMA F2000
22F250
IMA
F2000
n/a

The F2000 is a machine with linear transport with intermittent motion, for distributing liquid solutions in cylindrical containers. The machine is particularly suitable for the distribution of aseptic products, as it can operate in both conventional clean rooms and isotechnics.
The bottles are fed by means of an upstream feeding belt that introduces the bottles into the infeed starwheel.
Once the bottles have reached the infeed starwheel, they are positioned on the toothed belt on which the antistatic polyethylene moulded plugs and polyethylene contrast guides for positive linear transport of the containers are inserted using a 'quick-fit' system.
The dosing of the bottles takes place during the conveyor movement, the filling system is carried out by an external unit with 8 Felxicon peristaltic pumps, which performs the filling of the bottles by synchronising with their movement.
Once the bottles have reached the outfeed star, they are positioned on an in-line or 90° exit conveyor with independent drive controlled by an inverter.
The machine is equipped with a rejection station on a motorised belt with application of suction cups and vacuum on the exit starwheel for the bottles AND with a device for checking the actual rejection of the container.

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OPTIMA Blistering Machines OPTIMA COMPLETE SYRINGE FILLING LINE OPTIMA GROUPS • 2007
Blistering Machines OPTIMA COMPLETE SYRINGE FILLING LINE OPTIMA GROUPS • 2007
23-1129abcde
OPTIMA
COMPLETE SYRINGE FILLING LINE OPTIMA GROUPS • 2007
2007

COMPLETE SYRINGE FILLING LINE OPTIMA GROUPS • 2007
1. Debugger machine Bausch&stroebel model LFO 9060 from 2012
2. Belt under laminar flow Optima Inova
3. Robot for Tyvek removal Optima Inova model TRR •
4. Filling machine Optima Inova model H6-10
5. denester machine Optima Inova model SH260
6. inspection machine Brevetti Cea model k15\600 •
7. Renester machine Optima Inova model SN260 •
Syringes diameter 10.85
speed 400 pz\min

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COLANAR INOVATIVE SOLUTION Aseptic Filling and Closing Machines COLANAR INOVATIVE SOLUTION FSV 1111
Aseptic Filling and Closing Machines COLANAR INOVATIVE SOLUTION FSV 1111
23-1145
COLANAR INOVATIVE SOLUTION
FSV 1111
2012

FSV 1111 - Colanar Innovative Solutions is designed for filling syringes in the pharmaceutical field.
- Insertion of the syringe into the nest holder by the operator
- Process start via HMI Touch Screen
- Automatic positioning of the syringe
- Washing the syringe with nitrogen before filling
- Filling /inserting rubber stopper with vacuum capping
120 Volts

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BOSCH Aseptic Filling and Closing Machines BOSCH Complete line for ampoule Bosch  24.000 per hour  with Isolator from 2009
Aseptic Filling and Closing Machines BOSCH Complete line for ampoule Bosch 24.000 per hour with Isolator from 2009
*23-1059/23-1060/23-1061*
BOSCH
Complete line for ampoule Bosch 24.000 per hour with Isolator from 2009
n/a

Complete line for ampoule Bosch 24.000 per hour with Isolator from 2009 Composed of :
1) Ampoule filler under isolator
2) Depyrogenation owen for ampoules Bosch
3) Ampoule washing machine with different washing cicles
4)Air Handling Unit

1-Ampoule filler under isolator • Producer : Bosch • Model : ALF 4080 Year of manufacture : 2009 • Production : 400 ampoules per minute working range • Diameter : From 9 up to 30 mm • Height : From 60 up to 160 mm • Formats incluided :1 - 2ml • The machine comes with ISOLATOR and DEDICATE AHU AND CIP/ SIP IPC ( weigh control ampoules ) • The ALF series of machines meets all the prerequisites for modern ampoule production. The convincing line concept. • Wide experience, state-of-the-art know- how, highly developed engineering and Bosch quality – new dimensions for dependability, economy and flexibility with easy operator control. • The ALF series was configured in accordance with pathfinding, pharmaceutically compliant findings to provide a modern, ergonomic design that supplies the customer with maximum benefits. Decisive in this design is a basic ma-chine that can be equipped and retrofitted with various equipment units. These include: • In-process control system • Infeed and outfeed starwheel • Isolator version Work and production considerations: • Easy operator control due to the slim, tidy, clearly laid-out construction Easy cleaning. • All machine functions can be overseen, controlled and operated from one position at the front. • Clean Room compliance. • Drive and production segments are clearly separated: worktop right through. • The ampoules are transferred directly from the sterilizing tunnel to the ALF infeed belt. • Via a scroll conveyor and transfer wheel the ampoules reach the conveying system by means of which they are con-ducted through the work stations: gasflushing, filling, sealing. • Each filling point controls individually contactless scanning of the ampoule necks – "no ampoule – no filling". The ampoule necks are precentred by the draw-off grippers, the ampoule tips are then grasped and fed into a collection container. • During the sealing procedure post-gasflushing can take place. The filled and sealed ampoules are pushed virtually load-free into the outfeed magazine. Rotary slide pumps: • Bosch provides precision filling for parente- ralia with its proven rotary slide pump. Product- conserving and drip-free filling to the highest degree of filling precision are ensured for a wide range of different properties. • Bosch seal-free rotary slide pumps have easy vertical cleaning paths. Technical in the lead: • 3-part: rotary slide valve, pump cylinder,Pump piston. • Seal free. • Easy, vertical cleaning paths. ❒ • CIP/SIP capability. 2) Depyrogenation owen for ampoules Bosch Producer : Bosch Model : HQL 2440S Year : 2009 Production : 24.000 ampoules of 1 ml per hour HQL facilities are ideal for vial sterilization. This model is exceptional due to the lack of passage in the tunnel, which is the result of the laminar hot air flow process with its high degree of efficiency. Sterilization tunnels are used in pharmaceutical industry filling lines to sterilize glass containers before aseptically filling them. These tunnels use forced air at temperatures up to 350 °C. Bosch HQL drying and sterilization tunnels operate with unidirectional flow, with process curves of temperature progression and significantly reduced sterilization times. They guarantee the consistent precision necessary for validation, qualification, and reliable production capacity. Through a filter, the make-up air is introduced into the tunnel. Inside the tunnel, the air, drawn in by the fans, feeds the supply and cooling section through the pre-filters and the air particle filters in the separate areas of the tunnel. Using the laminar flow principle, the air flow is directed vertically in the containers. Below the conveyor, the air is directed back through a recirculation duct to the fan. The fans need fresh air for the heating section: laminar flow unit. The heating elements in the recirculation duct serve to heat the recirculation air to the preset temperature. Below the particulate air filters are heating elements that are output to a recording and temperature control device. The cooling section works with laminar flow. A fan in the cooling section draws the hot air under the conveyor belt. The volume of exhaust air is adjusted automatically. The tunnel is equipped with an automatic overpressure control in the cooling section. Modular system for tunnel assembly suitable for the required power range with optimal energy consumption. Construction according to GMP. Compatible container transport systems for stable and non-stable containers. Safe conveyor belts on the floor and side levels operated simultaneously. Excellent accessibility and ease of operation. 3) Ampoule washing machine with different washing cicles (water WFI - sterile air ) Producer : Bosch Model :RRU 3084 Year of manufacturing :2009 Production : 400 ampoules per minute Working range : Diameter : 9 - 30 mm Height : 60 - 145 mm Formats included : 1 -2 ml The Bosch RRU series of washers and dryers perform ultrasonic cleaning for fast and accurate removal of particulate matter. Its swivel design allows for a small footprint and ease of operation with fast and accurate removal of particulate matter and reliable feeding of small containers. RRU Bosch rotary heads will give you excellent results with gentle vial handling. They can be configured for a wide range of formats. Rotary washer ideal for cleaning vial bottles. Exceptional for its optimal accessibility, for example, and it is very easy to use. Processing ranges and capacities depend on individual containers, line integration, etc. Construction according to GMP; reduced size; safe transport of containers; high level of ultrasonic cleaning; stations for internal and external container washing; with the pumping station; fast format change.

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Bausch  Aseptic Filling and Closing Machines BAUSCH ATG under Isolator
Aseptic Filling and Closing Machines BAUSCH ATG under Isolator
23-983
Bausch
ATG under Isolator
n/a

NEW Bausch ATG Liquid Filling Line under Isolator. Never Used. Ready to be shipped and installed NOW.
With 12 Months of Warranty + Commissioning Service.
Ready to be shipped and installed NOW.
SPEED
2R - 9900/hr (165p/m)
6R - 6600/hr (110p/m)
Change parts available up to: 30R - 30,000/hr
Bausch ATG – Filling Line

• Machine 1: Bag, Lid and Line Remover
• Machine 2: Debagging station
• Machine 3: PUV light tunnel type 411
• Machine 4: Delidding machine
• Machine 5: Filling and stoppering machine type 534 - change parts available 2R/6R
• Machine 6: Crimping machine type 551 – change parts available 2R/6R
• Machine 7: Outside file washing machine type 309 – change parts available 2R/6R
• Machine 8: Labelling machine type 6034 (with dual tray discharge)
• Machine 9: Viable and non-viable monitoring system

ESCO GB LTD - Isolator

• Machine 1: Isolator + oRABS
• Machine 2: De-Bagging oRABS
• Machine 3: De-Lidding Isolator
• Machine 4: Filling and Stoppering Machine Isolator
• Machine 5: Crimping Machine Isolator
• Machine 6: Outside Washing Machine Isolator
• Machine 7: Glove Testing Units
• Machine 8: Glove tester

with following documentation:

• FAT Documentation
• SAT Documentation
• Installation Documentation
• Videos / Photographs
• De-commissioning Documents
• Quotations
• Layout Drawings
• Equipment Package
• HAZOP
• IQ OQ Documents
• Delivery Documents
• DDS

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CORIMA Aseptic Filling and Closing Machines CORIMA FSP1
Aseptic Filling and Closing Machines CORIMA FSP1
23-1230
CORIMA
FSP1
n/a

Filling and capping machine model FSP1 CORIMA MARCHESINI
Total mass of the machine. 650 kg
Power of electrical system in kW. 400V
Electrical installation
Main power supply: 400V
Fasi 3F+N+T
Frequency 50 HZ
Set power 2 kW
Air pressure 0.5%bar
Recommended temperature for the working environment 16°÷35°.
Fluids:
Nitrogen pressure 6 bar 5%
Nitrogen connection Ǿ 8mm quick connection
Products currently available
Working format:
Syringe Ǿ 10.85 mm Production rate: 2000 und/h
NEST DE 160 DE 1 ml Diameter 8.15 mm
NEST DE 100 DE 1 - 3 ml
NEST DE 64 DE 5 ml

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BOSCH Aseptic Filling and Closing Machines BOSCH MLF 3002
Aseptic Filling and Closing Machines BOSCH MLF 3002
24-1295
BOSCH
MLF 3002
1995

Bosch MLF 3002 intermittent motion filling and closing machine for injectable vials. Includes rotaty table for empty vials, 4 rotary piston filling heads (currently filling 100ml), stoppering inserter with bowl feeder, and closing system for ALU caps with bowl feeder. 90 degree reject to the rear of the machine, and product discharge in line with product flow. Suitable for containers up to 55mm diameter and up to 185mm high (double index), inserts and caps up to 36mm diameter.
Output approximately 6,000 containers per hour.

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CONTACTS

INTIMAC s.r.l.

Via XXV Aprile, 8

21054 Fagnano Olona (VA)

Italia

Tel. +39 0331 1693557

email: inti@intisrl.it

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