DLST/L Series (Class 100 - ISO 5) dry heat sterilizers are designed in accordance with cGMP Prescriptions to meet the multiple needs of the Pharmaceutical Industry and to perform the following treatments: Dry heat sterilization is an ecologically non-polluting process that does not generate waste or inconvenience problems for the environment or personnel. At the same time, the process fulfills the most stringent requirements for bacterial load reduction. Possibility of realization in execution suitable for continuous operation up to 300°C with the use of HEPA filters equipped with special sealant. Main applications: empty glassware (e.g., vials, bottles) stainless steel accessories (e.g., trays, machine parts) various moisture-fearing materials basic pharmaceuticals and thermostable chemical compounds non-aqueous liquids (e.g., oils, glycerins, etc.) The chamber is available in horizontal execution. Only components of the highest quality and reliability, available internationally, are used in the construction of De Lama sterilizers to ensure ease of replacement and maximum system life.
DEPYROGENATION TUNNEL BOSCH HQL 3240 HQL installations are ideal for the sterilisation of vials. This model is exceptional because of the low throughput in the tunnel, which is the result of the laminar hot air flow process with its high degree of efficiency. Sterilisation tunnels are used on filling lines in the pharmaceutical industry to sterilise glass containers prior to aseptic filling. These tunnels use forced air at temperatures of up to 350°C. Bosch HQL drying and sterilisation tunnels operate with unidirectional flow, with process curves of temperature progression and significantly reduced sterilisation times. They guarantee the constant precision required for validation, qualification and reliable production capability. Through a filter, make-up air is introduced into the tunnel. Inside the tunnel, the air, drawn in by fans, feeds the supply and cooling section through pre-filters and particulate air filters in separate areas of the tunnel. Using the laminar flow principle, the air flow is directed vertically into the containers. Underneath the conveyor belt, the air is directed back through a recirculation duct to the fan. The fans need fresh air for the heating section: laminar flow unit. The heating elements in the recirculation duct serve to heat the recirculation air to the preset temperature. Below the particulate air filters there are heating elements with an outlet to a temperature control and recording device. The cooling section operates with laminar flow. A fan in the cooling section exhausts the hot air under the conveyor belt. The exhaust air volume is automatically adjusted. The tunnel is equipped with an automatic overpressure control in the cooling section. Modular system for tunnel assembly suitable for the required power range with optimum energy consumption. GMP-compliant construction. Compatible container transport systems for stable and unstable containers. Safe conveyor belts on floor and side levels operated simultaneously. Excellent accessibility and ease of operation. Technical data
Length 2865 mm
Width mm 2200
Height 2630 mm
Weight Kg 2500
The machine was installed in 2011 and shut down in 2022. It is in perfect condition,
Equipment:
Internal chamber height 450 mm
Internal chamber width 450 mm
Inner chamber depth 1300 mm
Number and type of doors 2psv
Control and management system type OLIPYA/WP-TS
Design pressure 2.5 barg /250 kPA
Design temperature 139°C 412 K
Steam generator type DLSG/O/E/C-24
Steam generator output 33 kg/h
Steam generator design pressure 4.0 barg / 500 kPA
Steam generator design temperature 152°C / 425 K
Power supply (+/- 5%) 400 V - 50 Hz - Three-phase
Installed power 26 kW
Theoretical empty weight 1200 kg
Theoretical weight hydraulic test 1463 kg
Bosch Strunck depyrogenation tunnel model TLQ U22 from 1988
Producer Strunk (Bosch)
Modell TLQ U24
capacity max. 15000V/h
tunnel width 400mm
hot air filter feltproof
dimensions (approximately):
- tunnel L = 3,0m W = 1,3 m H =2,4 m; 2500 kg estimated
Air requirements:6 BAR
Voltage: 220 VOLT
Frequency: 60 HERTZ
Phase: 3+1
ENTRANCE ROOM
The inlet chamber can be divided into three volumes.
In the upper volume are installed: the inlet fan, the exhaust fan, the pre¬ filter and the HEPA filter.
The periphery of the filter is under vacuum because it is connected to the air exhaust area. No leakage can go to contaminate the vials.
In the intermediate volume is the transport system, the tunnel inlet door with the respective motor and potentiometer.
Removable panels allow access to the three volumes for cleaning and maintenance work.
HOT ROOM.
The structure of the hot chamber is similar to the inlet chamber. However, the hot chamber is thermally insulated and the air is recirculated. In fact, the chamber consists of two boxes, one inside the other. The two boxes are separated by a layer of insulating material that has a minimum thickness of 120mm and a maximum thickness of 150mm.
The inner box, which can be heated up to 4OO°C, is welded at a single point to the outer box to allow thermal expansion without causing damage to the structure.
On the right side, a door, filled with insulation material, gives access to the filter area, the fan, and the heating elements.
The fan motor is located outside the chamber, above the tunnel roof.
COOLING CHAMBER
The cooling chamber is similar to the inlet chamber, but the air is recirculated.
In the upper volume is the fan and HEPA filter. On the roof is located the balancing fan, which, through a duct, connects the cooling chamber to the supply fan intake area of the inlet chamber.
In the intermediate volume, on the service side, the cooling coil is installed. The water supply to the coil is regulated by a solenoid valve. A door moved by a motor divides the tunnel from the sterile chamber. The position of the door is detected by the potentiometer
Usable shelf area: 8.9 m2 (8 usable shelves of 914 mm x 1219 mm)
Shelf spacing 105 mm
These 2 elements should allow you to calculate the number of vials and the type of vials (>100
mm).
Condenser capacity : 150 kg of ice
Shelf cooling: 1.75°c/min with maximum attained at -53°c
Heating shelves: 2°c/min, max T°c shelves 65°c
ATM pressure at 0.1 mbar in 30 minutes
Maximum vacuum reached: 0.003 mbar
Pressure increase rate: 0.005 mb x l/s
double-door autoclave 1345 litres,
Via XXV Aprile, 8
21054 Fagnano Olona (VA)
Italia
Tel. +39 0331 1693557
email: inti@intisrl.it