+39 0331 1693557
inti@intisrl.it
Download of all our available used machinery
The PMA System comprises of three machines. It is the ultimate in versatility, with modular options for blending, high shear granulating and melt or wet pelletizing. The design maximizes product processing and contained handling. User-selected standard process modules are combined with advanced automation and cleaning-in-place (CIP) systems.
GEA Niro Pharma Systems Aeromatic Fielder mixing/drying system consisting of:
(1) GEA Niro Aeromatic Fielder high shear mixer, type PMA 1200.
Polished stainless steel construction,
Total capacity 42.37 cu ft (1200 liter), working capacity 31.78 cu ft (900 liter).
Measurements : 4’9” (1500 mm) , x 2’36” (725 mm)
1 Chopper. Lit with counter weight. On stand. Siemens control panel., year 2008. incl. integrated
For high shear pelletization, a special mixing tool is available to optimize the process and maximise the output.
Wet Pelletizing: This process uses a rotary atomizer spray to achieve excellent dispersion of binder liquid through the mix, and a special high-speed rotation blade for maximum movement of the product, for more efficient pelletization. A PTFE container-lining minimizes the need for ‘top and tailing’, even with the most cohesive of products. Studies have shown that the PTFE liner, unique to GEA can increase production efficiency by as much as 40%. Alternatively, an extruder may be used, similar to those used for the manufacture of pellets. In a typical set-up all ingredients are pre-blended in a container after dispensing. Depending on the extruder design the liquid can be added in the extruder or mixed separately to the correct consistency. The material produced by the extruder is now transferred directly into a continuous fluid bed where it is dried to the desired moisture level.
Melt Pelletizing: This is an exceptionally fast method of producing pellets in a single step. The active material and binder are mixed in binder form then heated until the binder melts. A single batch is processed typically in just 15-20 minutes, and needs no further drying.
(2) GEA cone mill,
(3) GEA Niro fluid bed dryer, type Sirocco 1200,
Working capacity 958 liter,
Rated for 150 PSI (10 bar), year 2008. Incl. controls. Include Cip System , explosions Valves included
Sizes :
Cardboard box :
Length: 250 mm - 450 mm
Width: 150 mm - 300 mm
Height: 170 mm - 325 mm
Length + Width: 400 mm - 750 mm
Flap: 75 mm - 150 mm
Product boxes :
Length ( stacker width direction ) 80 mm - 130 mm
Thickness (stacker height direction) 20 mm - 60 mm
Width (stacker lengthwise) according to case length
Automatic blister packaging machine designed for blister packaging pharmaceutical products such as dragees, tablets, capsules, etc.
50 strokes / minute
Film width: 254 mm / max
Pitch 180 mm / max
Packaging cycle: Heating - Stamping - Loading - Sealing with coding - Cutting - Pre-cutting
230-380 v 50 h Blister weight: 1800kg approx.
Seefried VACUMIX VHMS 1250 ointment processing plant
2 mixers 1250 litres net capacity, with agitators
1 preparation tank with 225 litres net capacity, with propeller agitator at the bottom
1 water tank 225 litres net capacity, without agitator
1 stainless steel working platform, approx. 10 m2
1 IPC control system with two operating panels, recipe mode, documentation.
The plant was used to produce gels for the manufacture of dialysis filter membranes. The plant was only in operation for about 12 months, after which production was stopped.
The plant is still set up as shown in a heated building and is in good condition, mechanically almost new.
Container 1 was used for the production of gel capsules. Equipment: with homogeniser and additional equipment.
Container 2 was used for melting masses for suppositories.
KILIAN Synthesis 500 WIP tablet press
Weight : 3950 kg
Version : EU/TSM / IMA - D
Technical Data :
Number of stations : 39
Mould type : Ronchi EU (IPT)D / Matrix E D
Max. tablet diameter 25
Filling chamber : 18mm
Drum rotation speed : min 10 - max 80
Production capacity : min 27,000 /hour - max 270,000 /hour
Compression force : 120 Kn
Machine weight : 2,600 kgh
Complete Line composed by :
- BLISTER MACHINE FOR AMPOULES FARCON FC320 WITH VISION SYSTEM SEA
VISION AND DIFFERENT FORMATS INCLUDE
- CARTONER CAM MODEL HV2 FOR AMPOULES
- CHECK WEIGHER INLINE
- MARCHESINI BOX MARKING MACHINE MODEL MS734 FROM 2008
- WRAPPING MACHINE PRB MARCHESINI FAR 2001 FROM 2004
- CASE PACKER PRB MARCHESINI MODEL SP FROM 2004
- PALETTIZER PRB MARCHESINI MINISTRATUS YEAR 2009
BLISTER MACHINE FOR AMPOULES FARCON FC320 WITH VISION SYSTEM SEA VISION AND DIFFERENT FORMATS INCLUDE Manufacturer: Farcon ( MARCHESINI GROUP ) Model: FC320 Year : 2002 For thermoforming trays for ampoules, vials, Maximum forming depth : 42 mm Speed : 45 cycles/min Maximum forming area: Film width 254 mm; Film pitch 220 mm Maximum cutting area: Film width 248 mm; Film pitch 210 mm Maximum production: 63000 ampoules (1 ml)/h Autmomatic ampoules feeder on trays pick and place system to pick up trays and place them on a conveyor Two-way conveyor Pneumatic network : - Pressure: 6 to 8 bar, - Connection: Ø 3/4". - Consumption: 500 Nl/min Hydraulic network : - Pressure : 1.5 to 2 bars - Connection : Ø 1/2" Gas - Temperature : 11°C to 15°C - Average consumption : 200 l/h Power supply : 400V 3-phase, 50Hz, 3A Power : 6kVA CARTONER CAM MODEL HV2 FOR AMPOULES : Model HV2 Year 2002 GUK leaflet folder Laetus Argus 4 bar code reader Material of machinable cases: Compact carton with a weight of 220 +/- 400 gr / m2. Cords and preattached cases. Closure: With hot melt Automatic ampoules trays feeder . Electrical Trifase altering 220 or 380 V 50Hz Motor power 3 Kw Motor power bovine pump 1.25 Kw Power transformer and service circuits 0.95 Kw Total power 5.20 Kw Air consumption Absorbed 17NL per minute at a pressure of 6 bar CHECK WEIGHER INLINE PRODUCER RAMSEY TECNO EUROPA YEAR 2000 Belt with air reject system. Includes gripper belts at feed. Complete with control panel WRAPPING MACHINE PRB MARCHESINI FAR 2001 wrapping machine prb marchesini far 2001 from 2004 automatic over wrapper equipment: 100 mm wide x 1200 mm long dual side pvc belt conveyor pushing station wrapping station sealing station folding station driven by variable speed safety guards pack capacity: pack dimensions: length: min. 60 mm - max. 210 mm width min. 60 mm - max. 250 mm height: min. 10 mm - max. 150 mm maximum output: 80 packs/minute power: 2,5 kw CASE PACKER PRB MARCHESINI MODEL SP Year 2004 Automatic Horizontal Case Packer, machine for the final packaging in cardboard, made in a way to ensure reliability, versatility and space saving. A really small size equipment with high production features. MAIN FEATURES: This is an automatic unit able to perform automatically and in a continuous cycle the grouping of products, their introduction into shipping cartons previously taken from stock, formed and positioned in such a way as to enable the mobile hopper and the pusher to carry out the filling, which completed the two groups of transport side, which serve to maintain the correct squaring, convey the same to the exit by passing it through the operating groups which carry out the closure on both sides by tape closing . The entire machine is equipped with safety sensors and plexi-glass safety doors. This unit can be easily changed over for different types of products including boxes, bottles, tubs and containers, and different size boxes. Electrical panel with PLC. Level control of boxes in stock, maximum load in power control, counters (packagings, working hours, etc.). TECHNICAL DATA Power absorbed Kw 3,18 Electric Frequency Hz 50 Voltage Volt 380 Pressure bar 6 PRODUCTION CHARACTERISTICS Production 12 cycles/min Carton sized range : min ( AxBxC ) 20x10x 75 max 550 x 130 x 290 Case formats min-max (Length x Width x Height) mm 200x120x100 mm 550x350x350 ( 600 ) mm PALETTIZER PRB MARCHESINI MINISTRATUS Year 2009 Model Minustratus Max speed 10 cycles per minute Format range A 150 - 600 mm B 100 - 400 mm C 80 - 610 mm Dimension pallet height Standard dimension 1665 Pallet dimension 800 x 1200 / 1000 x 1200 Electrical details 380-220V 50Hz Power installed 6 kW Air compress 6 bar Air consumption 0,7 NL/ per cycle
The machine has been designed to be inserted into all the modern phar-maceutical production lines.• Several options of the infeed system have been designed in order to sati-sfy most client demands.• The main machine turret is equipped with 24 spindles. The lower part ofthe spindle is rotated or stopped according to the inspection required.• Each container undergoes a series of inspections along the carousel bymeans of monochromatic CCD digitalcameras.• Each inspection station consists of acamera and its dedicated LED light source available from the bottom or fromthe rear.• An additional station for tip shape inspec-tion with its dedicated reject device canalso be supplied.• All the acquired images are sent directly to the PC and processed by adedicated vision system.• The container is accepted if all inspection results are received as positi-ve by the PLC.• The system works with Siemens WinCC scada.• Validation procedure can, if requested, be in compliance with CFR21part. 11.
Ampoule inspection with ongoing productioninside the main turret of the MCA 200
IMA ALU 200 Capper (Serial Number: F95057)
IMA F51 Vibratory Feeder
IMA Inkjet Libra Label Coder (Serial Number: LE0005)
IMA RT-120 48" Rotary Table (Serial Number: LA2155)
IMA ALU 200 Control Panel
IMA RT-100 40" Rotary Table (Serial Number: LA2156)
IMA HMI
Dimensions : 14198.60 x 1524.00 x 2438.40 mm - 3628.80 kg
Inspect system: Automatic
Container type: Vials, Ampoules, Cartridges
Speed: 12.000
The machine is designed for inspection of glass ampoules, both clear and amber, equipped with 3 cameras and formats for 2ml and 3ml ampoules.
A30 machine has been designed to be inserted downstream from filling and sterilizing lines and up-stream from labelling and packaging systems. Once loaded on the conveyor belt, the containers (ampoules, vials, cartridges) are sent to the inspection path, where all the inspections are carried out. Process control is totally automatic.
Each container undergoes a series of inspections, including particles, fill level, cosmetic inspections (optional), performed by high speed cameras. The integrated electrical cabinet contains all the elec-tronics which control the machine, including power section.
A swivelling operating panel equipped with pushbuttons and a touch screen PC provides the user in-terface, which allows the user to select or modify the inspection parameters and to print production reports; it also displays some diagnostic information about the state of the various parts of the ma-chine.
BASSINA MANESTY ACELA COTA 48
- spraying system
- air treatment system
- filter
- dust collector
CARTONER CAM MODEL HV2 FOR AMPOULES :
Model HV2 Year 2002
GUK leaflet folder
Laetus Argus 4 bar code reader
Material of machinable cases: Compact carton with a weight of 220 +/- 400 gr / m2.
Cords and preattached cases.
Closure: With hot melt Automatic ampoules trays feeder .
Electrical Trifase altering 220 or 380 V 50Hz Motor power 3 Kw Motor power bovine pump 1.25 Kw Power transformer and service circuits 0.95 Kw Total power 5.20 Kw Air consumption Absorbed 17NL per minute at a pressure of 6 bar
General description:
The CEA ATM 18/18 was conceived to be introduced in the modern Pharmaceutical production line.
It is placed after the filling and sterilization line, before the labeling and packaging line.
The ampoules and/or vials are loaded manually on the loading plane of the ATM machine 18 by trays. The output of the rejected and approved ampoules and/or vials are respectively collected in separate trays.
The base configuration of ATM 18/18 is built by:
Mechanical module: dedicated to the transport of ampoules and/or vials throughout the control route.
The electrical panel of each complete module of the power circuits, control circuit, motors, etc. is integrated in the mechanical module.
List of controls that can be executed by the machine:
a) Particle controls using various types of lighting (two stations)
b) Filling level and vial height (one station)
Formats 1-2-5 ml
Process description:
The process control is fully automatic. The ampoules and vials are subjected to a series of inspections carried out by cameras.
The ATM18 is intended for the automatic control (detection of impurities), by means of lighting, of liquid pharmaceutical products in glass containers (ampoules and vials).
The operator manually loads the ampoules or vials onto a conveyor belt; these are collected one by one and transported to the two rotation stations to move the liquid and possible impurities. Subsequently, the ampulla is blocked and a camera records a series of images at a distance of 20 ms from each other. By means of a controller, the first registered image is controlled with those that follow. If the images are different, the ampoule is rejected. The same procedure is repeated in two other stations similar to the one described. In the third station the level of the liquid is also controlled. Once the control is over, depending on the result, the ampoules are placed in two different trays and the driver extracts them manually.
Technical characteristics:
• Dimension ampoules and bottles: Diameter Ø from 9 to 18 mm total height up to 100 mm
• Mechanical speed: 18,000 vials/hour max. for 1 – 2 ml ampoule
• Rotation speed: continuously adjustable from 500 to 3000 rpm
• Power supply: 230V ± 10% 50/60 Hz 1Ph
• The Client must guarantee a voltage fluctuation of no more than 10%
• Absorbed power: 5 Kw
• Loading/unloading plane height: 900 mm (adjustable ± 25 mm)
• Dimension: mm 2460 x 1720 x 1740 h
• Weight: 1200kg
• Noise: ≤ 75 dB (A)
Via XXV Aprile, 8
21054 Fagnano Olona (VA)
Italia
Tel. +39 0331 1693557
email: inti@intisrl.it
