+39 0331 1693557
inti@intisrl.it
Download of all our available used machinery
Vector Model FML3 Developmental Fluid Bed Dryer (Year of Construction 2007)
With their standard drying, top spray and bottom spray capabilities, the VFC-LAB FLO-COATER® series are the most versatile lab-scale fluid bed systems available. The unique design of the combined product container/processing insert and integrated solution pump eliminates the need for costly "add-ons". The combined product container also allows for quick changeover and cleaning between processes. Portable, flexible, cleaning efficient and easy to operate, the VFC-LAB series is the perfect solution for your process development requirements. The Vector is a self-contained laboratory fluid bed unit. To offer fluid bed equipment capable of meeting specific requirements, yet versatile enough to cover all aspects of fluid bed technology, Vector employs a system concept.
Each component plays an integral role in the overall performance of a given process. Vector system. Vector systems consist of several basic components with many options to choose from. The basic fluid bed unit with insert. 8 litre product container for drying/granulation. electrical control panel HMI Peristaltic pump unit Exhaust/intake blower Heat exchanger The FL-Multi-3 provides a controlled environment for product to be prepared with a minimum of waste, damage and contamination under safe conditions.
TECHNICAL DATA :
Height 2445 mm
Width 1803 mm
Length 813 mm
Voltage 460 VAC , 60 Hz , 3 PH
Installed power 20 Kw
Highlights
• Complete ELAU upgrade with 15" TFT TouchControl screen
• Complete mechanical overhaul
• Lateral web control forming film
• Cutting and splicing table
• Splice detection
• 3 zone heating station
• Berlex feeding boxes with product level control
• Safety flap
• Camera inspection for product, print position and product verification after sealing
• Lid foil unwind stand from the rear to include cut and splice table, splice detection (inside and outside), low level monitoring, reversing shoulder and lateral web control
• Sealing station
• Contact station
• Embossing station
• Punch station
• Vacuum belt outfeed
• Upgrade to main pneumatics with air dump valve
Technical data
Max. output
1200 blister/min.
Foil width
min 150 mm, max 300 mm
ET index
min 130 mm, max 280 mm
MT index
min 30 mm, max 120 mm
Blisterlanes
max 3-lanes
Blister dimension length
min 30 mm, max 120 mm
Blister dimension width
min 60 mm, max 284 mm
Forming depth
max 10 mm (PVC foil) max 8/10 mm (Alu foil)
The 1200 tableting machines of the Medium range are ideal as workhorses for production of mono tablets manufactured by standardized processes. They have a manually-operated turret exchange system.
• Punch type EUD • Tablet output max. tablets/h : 120.000 • Pre-compr. force max. kN 80 • Compression force max. kN 80 • Tablet diameter mm 25 • Filling depth max. mm 22 • Tablet thickness max. mm 8.5 • Weight kg 2500 • Dimensions mm 900 X 1160 X 1875
Semi-Automatic Cap Welding Machine Rommelag Model SM950
Cap welding equipment is used where the BFS machine is producing a large volume parenteral container.
The bottle is sealed when leaving the machine. In order to allow the tight connection with the giving set spike after perforation a cap is sealed on top of the container.
The cap contains a rubber disc. The spike penetrates through the disc and the sealed bottle top. There is no contact between the rubber and the solution, eliminating the risk of particles generated by the rubber. The inside of the cap is sterile after terminal sterilization.
A transfer unit takes the bottles off the conveyor belt of the bottle pack machine and places them on the conveyor system of the welding machine This conveyor system loads the containers into the welding unit. Simultaneously the plastic caps are automatically made available.
Within the welding unit, the bottles and caps are fixed in position and plasticized at the joining point with the mirror welding unit. In this way, bottle and cap are welded together homogeneously without adding foreign material.
Dimensions and weight:
width 1.570 mm, length 4.600 mm height 2.500 mm
Weight 1.200 kg
Control cabinet:
Width 600 mm, length 1.200 mm, height 2.100 mm
Electricity:
Connected load 11 kVA
Consumption 7,5 kVA
Pneumatic:
Operation pressure 8 bar, oil free ; consumption 250 sl/min
Heat radiation 8-10 kWh
Capacity bottles/hour (manual feeding of bottles):
8 fold - 1.200/hour
10 fold - 1.500/hour
12 fold – 1.800/hour
Semi-automatic vertical cartoner CAM AV65
Semi-automatic machine with intermittent movements and vertical
transport of the carton. Cartoner suitable for cartons with closure by inserting 2 or alternating flaps, the product is inserted manually, the machine inserts the leaflet, codes the carton, closes the carton and ejects the product at the exit.
The frame contains all the mechanical controls.
The Cam AV cartoner was designed with the need for frequent format changeovers in mind. The operations required to process a product and/or another carton have been minimised, enabling very fast format changeovers.
Technical data:
- Mechanical speed per minute 15 / 70 units
- Motors 1 Kw
- Power consumption 1.5 Kw
- Air consumption 16.9 NI/1
- Air pressure 5/6 bar
OMAR's BF100 automatic blister machine works automatically with an alternating system, producing industrial-quality blisters. Product loading can be done manually by the operator or automatically using a universal 'Full Box' loader. The data setting system and machine control work cycles are carried out via an operator panel managed by LC Siemens
Main features
1. production with alternating system
2. 2 blisters per stop if the total size of the 2 blisters does not exceed 100mm, taking into account the 6mm gap between the blisters
3. vertical and horizontal perforation which can also be carried out simultaneously
4. possibility of installing a forming system with pre-punches
5. blisters made of alu-alu
6. blisters in pvc-alu
7. maximum blister format mm 120x100
8. maximum depth of alveoli mm15
9. production approx. 600-1600 blisters/hour (1 per stop) or approx. 1200-3200 blisters/hour (0°2 blisters per stop)
10. setting of data and working cycles with operator panel managed by PLC Siemnes(CFR21 compliance)
11. control system for angular position of camshaft rotation by absolute encoder with an accuracy of 360 pulses/revolution
12. temperature is controlled by 3 temperature controllers, 2 of which are dedicated to temperature control for forming and 1 for sealing
13. possibility of installing automatic loading
Technical specifications:
machine layout mm 2,850x1100x1800H 1350 kg
Tablet filling station Bosch Type GFK 130, dosing unti for capsule from 1998
Etichettatrice
Produttore: Pago
Modello: SYS 120 duplex
Conforme alle norme CE
voltage: 220/240 Hz50 / Amps 16 Phase: single
The CFS 1200 is a development-scale machine and is fully automated, GMP compliant and will fill and/or seal capsules using Capsugel's unique non-banding sealing technology at a rate of 1200 capsules/hour with liquid or semi-solid formulations. lt is specifically designed to enable formulation scientists to better exploit the potential of lipid-based formulations tor poorly soluble compounds. lt helps accelerate the development time frame, particularly tor Phase 1 studies, thereby achieving 'Faster Time to First in Man'
The CFS1200 is designed to fill and to seal two-piece capsules, with the filling material being either liquid or semi-solid.
Technical Specifications:
CFS 1200 dimensions:
Width 1000 mm x Height 930 mm Dept 600 mm weight 150 kg
Electrical:
Voltage 230V AC – 1 phase / 110 V AC 1 phase
Frequency 50 Hz / 60 Hz
Current 7 A max / 14 A max
Compressed air:
Air dry, oil free
Conncetion type 8x12x mm minimum
Pressure: 6 bar
Minimum operation pressure 4,5 bar
Production related specifications:
CFS120 compatible LICAPS sze 4/3/2/1/0/00EL/000 (only 1 sized parts set included)
GIMAT's 4-way horizontal mixers are made of painted carbon steel or AISI 304 or 316 stainless steel with surface treatments suitable for use.
Specially ribbed sheets of adequate thickness are used to resist the stresses present during powder mixing, which takes place quickly and homogeneously thanks to the special four-way reel with four cross-flows.
These machines are designed as powder mixers but can also be used as homogenisers for powders of the same category belonging to different batches.
The direct drive with bevel gear motor and bevel wheels integrated with a torsionally flexible elastic coupling, depending on variations in load conditions, guarantees high efficiency of the entire kinematic chain and very quiet operation.
The coupling built into all models dampens vibrations and reduces the maximum shock load, creating to all intents and purposes a true shock absorber for rotary motion.
The gear motor is controlled by a vector inverter in order to allow a gradual start-up of the mixer even at full load and to adjust its rotation speed according to the filling percentage and type of mix.
Accessories :
- Electric control panel.
- Support frame to lift the unloader off the ground
- Weighing system on load cells
- Provision for loading and unloading with GIMAT flexible spiral or rigid screw conveyor systems
- Mixers suitable for pneumatic vacuum loading
- Upper cover can be fully opened to optimise cleaning and product
cleaning and product change
- Anti-burst and flame-retardant panels for internal explosion venting
The Seidenader Type XS-2 from 2012 is an economical and user friendly machine for the inspection of particles in liquids, specially designed for small to midsize production applications. Both, moving and non-moving particles are detected with extremely high reliability.
The Seidenader XS uses light extinction or light scattering methods, depending on pro- duct and container type.
Advantages:
· No moving inspection components like
mirrors, lights, cables or cameras
· New generation of digital cameras with
8 mega pixel chip for high resolution
images
· Continuous motion
· Wide product range up to ø51.6mm/100ml
· Double module design for higher speeds or future upgrade
· Full IQ/OQ support package
· Integrated control cabinet and operator
interface
· Minimal false reject rate
Fields of application:
· Vials and ampules
· 1ml-100ml
· Clear liquids and suspensions
Standard inspection criteria:
· Moving particles, glass chips and fibres
· Non-moving particles in the bottom of the container
· Underfill
Formats 20R/15ml
50H/30ml
100H/100ml
20R/15ml
50H/30ml
100H/100ml
AFV 2010
FILLING AND CLOSING MACHINES FOR AMPOULES AND VIALS
The machines of this series are fully automatic filling and closing ma- chines for both ampoules and vials. They are rotary machines processing 1 or 2 containers at each machine cycle and reaching an output of up to 3000 resp. 6000 containers per hour.
Multifunctional applications
Thanks to their compact design and small footprint, these machines can be used both in laboratories and in medium-scale production situations.
Format changeover is quick and easy, so these versatile machines can be used for different types of containers and products.
The layout of the workstations and the design above the work surface promote laminar airflow. Virtually all parts are made from corrosion-resistant materials such as stainless steel and high-quality plastics.
The machine is easy to clean and maintain.
Clearly arranged, versatile work area
- Loading containers from trays or automatic transfer from sterilizing tunnel upstream
- Intermittent transfer to the star wheel
- Container registration by photo- electric sensors to control follow- ing work steps (no container - no dosing - no stopper)
- Opening ampoules (if closed ampoules are processed)
-Nitrogen flushing before filling
- Precise dosing with valveless rotary piston pumps
-Nitrogen flushing after filling
- For ampoules:
Nitrogen blanket during sealing Sealing by melting the stem and pulling off the ampoule tip - For vials:
Closing by inserting rubber stoppers
- Discharge into trays or transfer to a machine linked downstream
Valveless rotary piston pump(s) - self-priming and precise
The dosing station is equipped with either one or two valveless rotary piston pumps. These high-quality, precision pumps comprising only two parts guarantee utmost dosing accuracy. These pumps are simple to remove, install, clean and sterilize as are all the parts in contact with the product.
Depending on the product to be filled, either stainless steel or ceramic pumps can be supplied.
Dose adjustments within the pump volume can be made by increasing or reducing the pump stroke.
Both the central dose adjustment and the fine adjustment for each pump are made mechanically with setting spindles. They are equipped with digital position displays ena- bling the dosing quantities to be repeated, so that they can be repro- duced with the same accuracy at any time.
Tried and tested
The ampoules are sealed by fusing the glass and pulling off the tips of the ampoule stems.
The fuel gas and oxygen mixture produces a constant burner flame. The gas supply can be set indivi- dually on the respective flow meter for each work station.
If the flame goes out, the gas supply is shut off automatically.
The ampoule stems are heated in two steps and then as the glass is fused to a dome the tip is pulled off and discarded into a bin. The heat generated by the sealing process is drawn out of the work area by an extraction system.
The closures are fed to the closing station by a sorting bowl and a track vibrator.
Technical details : Output 6000/h Ampoule Sixe Range : max 23mm Ø / Max 180 mm Vial size Range : max 30 mm Ø / Max 110 mm Dosing range : 0.15 – 28 ml Electrical supply 230/400 v – 50 hz – 1.5 kw
The STMC Compressed Steam Distiller, (system also described as “steam recompression distiller” or “steam thermocompression”, or even more generically “thermocompression still”, produces distilled water suitable for pharmaceutical applications (A.P.I.) and parenteral preparations (LVP, SVP). It is an ideal technology for any injectable product based on WFI (Water For Injection) and for special solutions where both quality factors (such as sterility and elimination of pyrogens and low molecular weight chlorinated solvents) and economic factors (low management costs) are critical for the competitiveness and success of the pharmaceutical process.
Voltage 400 V 50Hz Power 46 kW Compressed air 6 bar NL/min 3 Max steam heating 3 bar Weight 4100 Kg. With Bram Cor accumulation tank model STOC WSTP 10000 The BRAM-COR product range also includes a complete selection of Mod. STOC tanks/vessels for the collection of both pharmaceutical (WFI-PW-HPW) and process water. Traceability, material and component certification are values of all BRAM-COR installations. Strict welding and sanitary piping control procedures are applied in the production of the vessels, with non-destructive testing and in accordance with international standards for pharmaceutical equipment. Basic feature of all BRAM-COR tanks is that they are completely washable. In addition: Surfaces and components in contact with the products are certified in mirror polished AISI 316L stainless steel (Ra ≤ 0. 4 μm)Construction ‘Tank in Tank’ Vertical design Heating/cooling jackets with AISI 304 satin steel finish Technical data: Tank capacity 10707 litres Double jacket capacity 694 litres Max operating temperature tank 143 C° Max operating temperature jacket 143 C° Hydraulic test pressure tank 5 bar Hydraulic test pressure jacket 5 bar Material AISI 316L Pressure safety valve 2.5 bar Including water distribution pumps
The Evaporation Column is designed to minimize steam velocity to avoid entrainment of water particles, which are separated from the steam by a special separator. In a double tube plate heat exchanger, the heat from the steam heats the pretreatment water by heating it above boiling temperature, generating pure steam which expands in the evaporation column. The average heating of the DTS exchanger is usually determined by the industrial steam of 100 to 120 psig (6 to 8 bar).
Voltage 400 V 50Hz Power 1.1 kW Compressed air 6 bar NL/min 2 Max steam heating 6 bar Weight 1000 Kg.
- Drinking water release pump for water softeners
- Inlet and outlet drinking water pressure gauge
- N.2 glass fiber tanks with ion exchange resins
- Polypropylene tanks with delivery pump
- Sweetened water filtration and pre-filtration system Manufacturer: FLUXA FILTRI SPA Model: 5FA3S50 Serial: SN-R1150
- Design pressure: 10bar
- Design temperature: 80°C
- Hydraulic test pressure: 11.3bar Capacity: 34,91liters Quantity of filter elements. : 5x30"”
- 100lt polypropylene container for sodium metabisulfite with feed pump.
This water pretreatment comes with the tank (24-1716)
Accumulation tank Bram Cor modello
STOC PSSA 3000
The BRAM-COR product range also includes a complete selection of Mod. STOC tanks/vessels for the collection of both pharmaceutical PW-HPW) and process water. Traceability, material and component certification are values of all BRAM-COR installations. In the production of the vessels, strict procedures are applied for welding and weld control.
welding and sanitary piping control procedures with non-destructive testing and in accordance with international standards for pharmaceutical equipment are applied in the production of the vessels. Basic feature of all BRAM-COR tanks is that they are completely washable.
In addition:
Surfaces and components in contact with the products are certified in stainless steel AISI 316L polished
stainless steel AISI 316L mirror polished (Ra ≤ 0.4 μm)
Tank in Tank’ construction
Vertical design
Technical data:
Tank capacity 3649 Litres
Via XXV Aprile, 8
21054 Fagnano Olona (VA)
Italia
Tel. +39 0331 1693557
email: inti@intisrl.it
