+39 0331 1693557
inti@intisrl.it
Download of all our available used machinery
climet CI 750t
Particle Counters
climet CI 750t
Particle Counters
P250 Production scale pharmaceutical mixer
Mixing.Granulating.Production on large scale.
Your main benefits
Automated cleaning
Easy integration of Fluid bed processors
Integrated remote service
Combination of machine frame and lifting device
DIOSNA-Toollift for inspection of shaft seals (option)
Highly efficient mixing tool and bowl design made by DIOSNA
Optimise your production plant with your new high-performance pharmaceutical mixer. Discard complicated cleaning processes and varying mixing and granulation quality. Simplify your production processes thanks to the ideal mixer bowl access via the stable operating platform.
The Marchesini Tonazzi Poly 900 is an automatic machine with intermittent movements and vertical case transportation.
Case packer suitable for opening and filling cases with interlocking closure with three equal or alternating flaps, inserting a product fed manually directly into the open case, closing it and unloading it at the exit.
Main characteristics
The design of the machine ensures high quality production, based on proven experience in this field. It has the advantage of requiring minimum space while offering an adequate structure and safe performance. It is manufactured in compliance with safety standards and the machines are supplied with the CE mark.
Product feeding
The product is fed manually, directly into the vertically positioned tray with all the upper flaps open. Product feed height from 920 to 1120 mm, depending on the length of the tray.
Tray packaging section
• Motorized carton magazine, complete with minimum load sensor, at a height of approx. 750-870 and a length of 880 mm. Simplified adjustment of the magazine guides with millimeter scales;
• Unloading of the packaged cartons at a height of approx. 870 mm;
• The box is picked up from the magazine by means of a dual action system: pneumatically with suction cups and mechanically with an opening arm. Check that the box has been picked up from the magazine;
• After removal from the magazine, the carton is inserted directly between the transport teeth of the Cartoning Machine, which keeps the carton in perfect shape and transports it to the various work stations;
• In the first operation, the carton is closed at the bottom. It remains open at the top to allow the product to be inserted. The carton is then automatically closed at the top as well;
• A sensor detects the presence of the box in the magazine and if it is missing the machine stops;
• A control sensor detects the presence of the box to count the number of pieces produced;
• A further control detects the presence of the product, and if it is missing the machine stops to avoid the packaging of empty boxes;
• Automatic unloading of closed boxes, with ejector, onto an output table equipped with a sensor to check their correct position, which avoids jams in the box transport chain of the machine.
Technical data
Format data
• A: Min 15 mm - Max 120 mm
• B: Min 15 mm - Max 90 mm
• H: Min 50 mm - Max 250 mm
Range of folded leaflets
• Min 15 x 100 mm - Max 50 x 200 mm
Maximum mechanical speed
• up to 90 beats/minute
• The production speed always depends on the feeding system and the product features, as well as on the product configuration and the accessories added to the standard machine.
Production
• 80 cartons/minute
Output height
• 870 mm
Inspection Machine Seidenader V90-AVSB for prefilled syringes
From the infeed system, the product is conveyed through the inspection cabin on a continuously or intermittently moving transport system, consisting of a dual chain system fitted with white or black rollers. Each roller rotates on two precision roller bearing assemblies. The rollers are supported between dual conveyor chains.
Several lighting systems are available on option: A white light source provides diffused illumination from behind the rollers to allow inspection against both a white background (light source) and a black background (the rollers) or vice versa to meet GMP regulations.
Alternatively, highly concentrated halogen light can be shot through the bottom or shoulder of the containers, to reach the "Tyndall Effect". In addition to these lighting systems, mirrors, a magnifying lens and polarisation filters are available to optimize the inspection and to support the operator.
The product passes through the inspection cabin in front of the operator. This arrangement permits the inspection of the entire outer surface of the product.
The rejected product is easily removed either by hand or by an automatic reject system operated by infrared sensors.
The product is fed out of the inspection cabin, brought into upright position and is then transferred into various discharge systems: accumulation tables or trays.
Operators: one.
Output: max. 150 objects/min/lane.
Construction: stainless steel.
Mode of operation: continuous or intermittent (switch).
Voltage: 230 V, 0.8-1.4 kW, 50 Hz standard (all desired voltages possible).
Working height: 900 mm ± 50 mm.
Dimensions: ca. 2300 x 1000 x 1700 mm.
Weight: ca. 550 kg net.
Automatic Vial or Ampoule Leak Detection Machine Bosch KLD1042 from 2002
Diameter of ampoules min./maxi.: 10 - 32 mm
with form parts 3 ml / 5 ml / 10 ml /12 ml / 15 ml / 20 ml / 25 ml
Bosch AIM 296 inspection machine for ampoule
Automatic machine for vial inspection.
Year 2003
Toscana filling and capping line, Ticino 1T – 200 labeling machine, INK-JET marker, and rotating table
Composed of
1) Toscana Automazioni Industriali filling and capping monoblock (2021)
Model ARNO R8MG/T3 AUX
Installed power 8 kW
Dosing adjustment from 100 ml to 5,000 ml
Dosing system: magnetic flow meters
No. of dosing heads
No. of capping heads 3
Cap feed: automatic with automatic distributor
Closing system: Pic&place with magnetic clutch
H. Conveyor belt 950 mm +/- 30 mm
CE + ATEX 3 G construction (Zone 2)
Speed:
format F1 – Volume 1000 ml – 30 / 35 pieces/min
format F2 – Volume 500 ml – 45 / 50 pieces/min
format F3 – Volume 100 ml – 45 / 50 pieces/min
2) Automatic labeling machine Model Ticino 1T-200
Formats and application: SEMI-WRAP: Formats F1+F2
FRONT: F3
Label diameter: Min 25 mm – Max 200 mm
Minimum distance between labels 3 mm
Minimum distance from edge
Label length Min 20 mm – Max 300 mm
Machine speed:
Front and/or back: 60 pcs/min with 50 mm long label
Wrapping: 50 pcs/min with 100 mm long label
30 pcs/min with 250 mm long labels
Pre-set for Industry 4.0
With bottle-label format change: F1 – E 1 / F3-E3
3) Ink-jet marker with U2-PRO cartridge technology
From 1-4 print lines
4) With 1.20 mm rotating accumulation table
The test instrument is a small and lightweight portable unit.
The instrument provides the ability to perform either a forward flow test, bubble point test. Combined forward flow and bubble point test, water intrusion testo or leak test. The filter can be tested in place or of-line and its performance capacity remains unaffected by the test when suitable protocols are followed.
The instrument provides direct flow measurement of the filter under test. This measurement is independent of upstream volume over a wide range. Extensive internal Self test feature and use of high precision components virtually eliminate the possibility of significant measurement errors. The instrument is connected upstream of the filter under stress. The measurements are, therefore non-invasive of the downstream side of the filter and risk of contamination is eleimnated.t his is particularly important in installations where the filter has been sterilized before integrity testing.
OMME labeling machine Model: Master.8T 1S.2E from 1985
TOFFLON - Liquid Filling Line
NEW, NEVER USED WITH 1 year warranty from OEM
TOFFLON BOTTLE FILLING LINE
Description
Complete Isolator filling Tofflon line for both filling vials with sterile liquid and Lyophilization.
• The line has never been used, waiting for the FAT.
• 6R vials format included.
• Line speed: 200 vials/min. (6R).
• Max LYO load: 43.300 (6R) vials.
• OEB5 compliant.
• One year OEM warranty is included.
Available the direct support by the OEM for FAT, SAT, IQ, OQ and installation/commissioning globally.
The line can be customized and other formats are available directly by the OEM.
The line is composed by:
1. Rotary Washing Machine - FW03060
2. Sterilizing Depyrogenation Tunnel - FT01201
3. Vial filling and stoppering machine - FF0606
4. Capping Machine - MFC0230
5. Rotary Washing Machine - FE01048
6. Fixed Automatic Loading and Unloading Systems - ALS-Plus-12/15
7. Lyophilizer - LYO-20 (CIP/SIP) - RBR Type
8. Pharmaceuthical Isolator - Isolator-CS
KEY FEATURES OF STILMAS PSG-DTS
Immediate start-up: pure steam is immediately available thanks to the ‘Accumulator boiler’ technology design. The unit can go from standby to full capacity in just a few seconds
High flexibility: production capacity can be automatically varied from 0 to 100% according to demand
Unique purification system: gravitational purification principle for better steam purity guarantee
High-quality steam: the quality of the steam produced is constant in terms of pyrogen content, heating value and drying fraction, regardless of pressure and production flow rate
Simple and clean mechanical construction: the decontamination chamber without deflectors or defrosters ensures optimum inspection capability and minimises the risk of corrosion for a longer service life of the equipment.
Extremely low maintenance. No moving parts, expansion joints or mechanical seals
Compact construction and low height. Little extra headroom is required for dismantling and inspection.
OPERATING PRINCIPLE
The design of STILMAS PSG-DTS pure steam generators is based on thermosiphon technology. The system consists of two parallel bodies: the heat exchanger and the evaporator/decontamination column. The feed water is fed to the decontamination column (main body) while the industrial steam is fed to the support side of the heat exchanger. The industrial steam heats the feed water to the evaporation temperature, creating a strong circulation inside the two bodies.
The steam develops in the evaporator where its low speed and the height of the decontamination column eliminate any possible entrainment of impure water droplets. A pressure transducer, installed in the evaporator, controls the entry of industrial steam into the heat exchanger, thus ensuring a constant pressure of the pure steam produced. The feed water flow is controlled by a level transmitter installed in the evaporator.
REDUCTION OF NON-CONDENSABLE GASES (NCG)
Stilmas has developed two alternative solutions to meet the NCG requirements of EN 285.
The first solution consists of an intermediate tank in which the preheated feed water is sprayed, separating the liquid from the gas, which is then extracted to the outside.
This solution can adapt any clean steam generator to enable the NCG content to be achieved.
The second solution, Stilmas Gasbuster®, is integrated into the PSG. The degassing process occurs when the preheated feed water enters the decontamination column and is sprayed, separating the liquid from the gas, which is then extracted by a small flow of clean steam.
With both solutions, Stilmas PSG can provide NCG contents much lower than those required by international standards.
The plant is made entirely of AISI 316L stainless steel. The standard finish of the active surface is smooth and flush with passivation; mechanical or electrochemical polishing can be carried out on request.
The heat exchanger is of the shell and tube type with double sheet metal construction; the tubes expand onto the plates, avoiding any welding for a totally hygienic construction and better resistance to expansion stresses.
The design and construction of the decontamination chamber, which is a completely empty column, ensure the best inspection capability. The absence of welds in this area drastically reduces the risk of corrosion, ensuring a very long service life for the equipment.
The overall design of the construction, together with the decontamination process described, ensures a very compact design and requires extremely limited space for maintenance.
400V, 50 Hz, ph: 3+N+T
Fluid capacity 200
design pressure 6 bar
design temperature 165
hydraulic test pressure 9 bar
Via XXV Aprile, 8
21054 Fagnano Olona (VA)
Italia
Tel. +39 0331 1693557
email: inti@intisrl.it
