+39 0331 1693557
inti@intisrl.it
Download of all our available used machinery
Tabletpress Manesty Betapress
7,5 tablets per minute x’100
Year 2001
The max. infeed height is 830 mm (+- 50 mm) and the discharge height is 900 mm (+- 50 mm).
Format range collation (mm): Length 80 – 300
Width 65 – 190
Height 20 – 155
Film width (mm): 30 – 450
Single product range (mm): Length 65 – 190
Width 15 – 300
Height 15 – 90
Format change: 5 - 15 minutes (depending on product)
Output cycles: Approx. 40 cycles / min. (depending on product)
Automatic medium-speed vial washer for pharmaceutical and biotechnology applications
Range of vials : 2-100ml (format parts are required)
Production : Up to 100 vials per minute according to vials size
Change : Change from 20 minutes to a different vial format
Characteristics
• Typical batch size: 10,000-25,000 vials
• 8 vial holders that can hold up to 7 vials in the neck
• The vials are fed to the vial carriers by a feeding transmission belt
• The vials come out of the washing machine in a single row
• Rotating feeding table with automatic loading of the vials on the vial holders
• A transparent cover allows visual verification of the washing process.
• There are safety provisions to prevent water spraying when the cover is not located above the washing chamber.
• Dedicated media collectors (1 for water, 1 for air)
• Intermittent spraying and automatic lid lift mechanism
• GMP design: all stainless steel 304 / 316L
• La unidad principal es servoaccionada
• Intrinsically designed for the reduction of 3 log endotoxins
• PLC that works together with an HMI operator interface
• Each vial format has a "recipe" selected by HMI with specific settings for spray time and indexing time to help reduce water consumption.
• No penetrating nozzles, no glass breakage, less particle generation
• Self-draining after the end of the batch
• The internal surfaces are electroply polished.
• Orbital welding is used whenever possible
• The piping system is designed to work from highest to lowest to avoid water stagnation.
• Silicone seals are used throughout the piping system.
MICRODISING MACHINE ROMACO WITH CRIMPER MACHINE :
The Romaco Macofar model Micro 9 from 2013
Is a machines suitable for filling sterile pharmaceutical powders into vials under aseptic conditions. The Micro range of intermittent motion machines offers mechanical speeds ranging up to 9,000 vials per hour. They are renown for their reliable performance in aseptic lines for dosing sterile powders into round glass vials sealed with rubber stoppers. Designed for cGMP compliance, due to their balcony design, the Micro machines are recognized worldwide as leading powder microdosing machines, carrying on the decades of Macofar tradition.
Highlights
simple, fast and repeatable changeover.
• Automatic height adjustment of filling and closing groups, no manual adjustments required.
• Product format data is recorded in an electronic database and can be recalled via the touch screen.
• Nitrogen flushing before, during and after filling
• Liquid filling group for media fill test • Air drying unit to reach a controllable humidity percentage in the filling area.
• Vertical laminar flow over the dosing and stoppering stations with recycle
Technical Data
Speed up to – single dose (vials/hour)* 9.000
Vial dimensions diameter (mm), min. – max. 16-52
Vial dimensions height (mm), min. – max. 35-110
Minimum dose (mg)* 20 (no C.W.)
Maximum dose with single dose (mg)* 1,500
Dosing disc One single
Dosing port per disc 12
Power consumption (kW)* 9
Compressed air for powder ejection (l/min) 70
Vacuum pump (m3/h) 100
Including rotary table
Capping machine for vials Romaco Model CSP12 From 2013
CSP capping machines offer the latest state-of-the-art technology for vials sealing after they are filled with injectable drugs. They are suitable to handle various types of caps and have been developed respecting the most recent regulations associated with aseptic processing.
Fixed blade
Each vial entering the machine is locked in place by a bottom lifting and rotating plate and a fixed idle top plate; during the rotation a stationary side blade bends the cap bottom, sealing the vial.
Key Benefits
• Extremely compact footprint
• Mechanical design with minimal number of particles generated by caps (suction system of particulates produced during capping is an available option)
• Caps feeding location maximizes vials protection from non-viable particles
• Easy access to ‘white’ and ‘grey’ areas
• Easy cleanability of ‘white area’ surfaces
• Quick and easy removal/assembly of cap contact parts
• Very quick and repeatable semi-automatic size parts change-over with minimum manual interventions
Technical data
Vial diameter (with Alu-caps and flip-off), in mm 16 – 53
Vial height (with Alu-caps and flip-off), in mm 40 – 160
Mechanical output pieces/h 10.000
Closing Head 12
Motion continuous
Rated power in Kw 2.5
Some packaging materials require 100% integrity testing according to Annex 1 of the EU GMP guidelines. The Wilcomat Leak Detector is a high-speed inspection system, used to meet these requirements and not to reduce production. WILCOMAT is a Leak Detector for a wide range of products such as vials, ampoules, syringes, blisters and much more.
The LFC method provides a highly sensitive 100% leak test at high production speeds for liquid filled and lyophilized primary packaging containers. By means of the patented force measuring system the differential force of blister cavities or bags are measured in a vacuum chamber. This method safely identifies gross or fine leaks. During the testing process, the test parameters and the test results are displayed on the display. As with other differential pressure methods, the LFC method is based on a gas exchange between the container and the test chamber. In order to test liquid filled containers, the LFC method operates at a deep vacuum level. This vacuum level allows liquids to vaporize and requires the use of custom, proprietary sensors developed by WILCO to make the precise differential pressure measurements. The LFC method is optimized to check for leaks in both the headspace as well as the liquid phase of a container.
Inova 2-piston liquid bench filler
The Marchesini Tonazzi Poly 900 is an automatic machine with intermittent movements and vertical carton transport.
A cartoner suitable for unrolling and filling cartons with even or alternating three-flap interlocking closures, inserting a manually fed product directly into the open carton, closing it and unloading it at the outlet.
Main Features
The machine's design provides for high quality output, having utilised proven experience in this field. It has the advantage of requiring a minimum of space while offering adequate structure as well as safe performance. It is manufactured in compliance with safety regulations and the machines are CE marked.
Product Feeding
The product is fed manually, directly into the case, which is vertical with all upper flaps open. Product feed height from 920 to 1120 mm, depending on carton length.
Carton section
- Motorised carton magazine, complete with minimum load sensor, at a height of approx. 750-870 mm and a length of 880 mm. Simplified adjustment of the magazine guides with millimetre scales;
- Unloading of packed cartons at a height of approx. 870 mm;
- The carton is picked up from the magazine by means of a double-action system: pneumatic with suction cups and mechanical with an opening spreader. Control of the removal of the case from the warehouse;
- After unpacking, the carton is inserted directly between the transport teeth of the cartoner, which keeps the carton in perfect shape and transports it to the various work stations;
- In first operation the cartoner is closed at the bottom. On the top it remains open to allow the introduction of the product. Then the case is automatically closed on top as well;
- A sensor detects the presence of the carton in the magazine and stops the machine if the carton is missing;
- A control sensor detects the presence of the carton for counting the produced pieces;
- A further control detects the presence of the product, and if it is missing, the machine stops to prevent the packaging of empty cartons;
- Automatic unloading of closed cartons, with ejector, onto an outlet table equipped with a sensor to check their correct position, which avoids jams in the machine's carton transport chain.
CTechnical data
Format data
A: Min 15 mm - Max 120 mm
B: Min 15 mm - Max 90 mm
H: Min 50 mm - Max 250 mm
Folded brochure range
Min 15 x 100 mm - Max 50 x 200 mm
Maximum mechanical speed
up to 90 stops/minute
The production speed is always dependent on the feeding possibility and product characteristics as well as the configuration of the product and the accessories added to the standard machine
Production
80 cartons/minute
Output height
870 mm
Used Uhlmann thermoforming blister packaging machine, model UPS 4
Year: 2002
Min. - Max. Forming width - 62 - 226mm
Cycles - 15 - 50 cycles/minute
Forming depth - PVC - 12mm
ALU - 10mm Blister
Format - Min. - 60mm Max. - 140x39mm
Punching Area - Length - 226mm
Width - 284mm Forming Film width - Min. - 100mm Max. - 298mm
Lidfoil Width - Min. - 100 Max. - 298
Tooling - PVC/Alu –
Blister line size 39x94mm Alu/Alu
Machine Control- PacControl version 2.17 Camera
Cette polisseuse de gélules et/ou de comprimés d'occasion est construite en acier inoxydable.
Polisseuse de gélules et de comprimés en acier inoxydable pour l'industrie pharmaceutique. Brosse de polissage et brosses neuves. Etat neuf. 3 phases 10 ampères. Contrôleur de vitesse variable.
Marque : Kosan
Modèle no : Luminer II
Longueur : 1200
Largeur : 600
Hauteur : 1500
Moteur : 3ph
Logopak Model 410 III TB from 2012 accurately prints and applies labels in real time, which is of particular benefit when applying shipping address labels in the e-commerce sector, because real-time printing excludes misalignments.
benefits:
• fast and efficient labelling
• durable and low-maintenance
• high operating comfort / easy handling
• 100% electronically controlled for excellent results
• direct thermal or thermal transfer printing of labels up to A5
• internal database, error diagnosis, and many more clever features
• works as a stand-alone solution or integrated in existing networks
Characteristics:
• running length: 600 m
• outer diameter: 350 mm
• print resolution: 203 or 300 dpi
• label width: up to 165 mm
• up to 120 labels per minute
• 30 different applicators available
• 10" touch screen
• labels up to A5
• enclosure: optional
The Marchesini Tonazzi Poly 900 is an automatic machine with intermittent movements and vertical carton transport.
A cartoner suitable for unrolling and filling cartons with even or alternating three-flap interlocking closures, inserting a manually fed product directly into the open carton, closing it and unloading it at the outlet.
Main Features
The machine's design provides for high quality output, having utilised proven experience in this field. It has the advantage of requiring a minimum of space while offering adequate structure as well as safe performance. It is manufactured in compliance with safety regulations and the machines are CE marked.
Product Feeding
The product is fed manually, directly into the case, which is vertical with all upper flaps open. Product feed height from 920 to 1120 mm, depending on carton length.
Carton section
- Motorised carton magazine, complete with minimum load sensor, at a height of approx. 750-870 mm and a length of 880 mm. Simplified adjustment of the magazine guides with millimetre scales;
- Unloading of packed cartons at a height of approx. 870 mm;
- The carton is picked up from the magazine by means of a double-action system: pneumatic with suction cups and mechanical with an opening spreader. Control of the removal of the case from the warehouse;
- After unpacking, the carton is inserted directly between the transport teeth of the cartoner, which keeps the carton in perfect shape and transports it to the various work stations;
- In first operation the cartoner is closed at the bottom. On the top it remains open to allow the introduction of the product. Then the case is automatically closed on top as well;
- A sensor detects the presence of the carton in the magazine and stops the machine if the carton is missing;
- A control sensor detects the presence of the carton for counting the produced pieces;
- A further control detects the presence of the product, and if it is missing, the machine stops to prevent the packaging of empty cartons;
- Automatic unloading of closed cartons, with ejector, onto an outlet table equipped with a sensor to check their correct position, which avoids jams in the machine's carton transport chain.
Technical data Dati formato • A: Min 15 mm - Max 120 mm • B: Min 15 mm - Max 90 mm • H: Min 50 mm - Max 250 mm Gamma prospetti piegati • Min 15 x 100 mm - Max 50 x 200 mm Velocità meccanica massima • fino a 90 battute/minuto • La velocità di produzione è sempre dipendente dalla possibilità di alimentazione e caratteristiche del prodotto nonché dalla configurazione del prodotto, nonché dagli accessori aggiunti alla macchina standard Produzione • 80 astucci/minuto Altezza uscita • 870 mm
Alexanderwerk Granulating Sieve Type R-300
- Grater / shredder sieve for granulates (1x)
- Sieve dimensions dia. 300x130mm
- Sieve perforation dia. 10mm, Without hopper
- Input dia. 270mm
- Motor 3.6 KW, 230/400 Volt (Ex)
- Material Stainless steel
Floor area 1.5x1.0 M
Total height 1.55M
Weight 340 KG
GIMAT's 4-way horizontal mixers are made of painted carbon steel or AISI 304 or 316 stainless steel with surface treatments suitable for use.
Specially ribbed sheets of adequate thickness are used to resist the stresses present during powder mixing, which takes place quickly and homogeneously thanks to the special four-way reel with four cross-flows.
These machines are designed as powder mixers but can also be used as homogenisers for powders of the same category belonging to different batches.
The direct drive with bevel gear motor and bevel wheels integrated with a torsionally flexible elastic coupling, depending on variations in load conditions, guarantees high efficiency of the entire kinematic chain and very quiet operation.
The coupling built into all models dampens vibrations and reduces the maximum shock load, creating to all intents and purposes a true shock absorber for rotary motion.
The gear motor is controlled by a vector inverter in order to allow a gradual start-up of the mixer even at full load and to adjust its rotation speed according to the filling percentage and type of mix.
Accessories :
- Electric control panel.
- Support frame to lift the unloader off the ground
- Weighing system on load cells
- Provision for loading and unloading with GIMAT flexible spiral or rigid screw conveyor systems
- Mixers suitable for pneumatic vacuum loading
- Upper cover can be fully opened to optimise cleaning and product
cleaning and product change
- Anti-burst and flame-retardant panels for internal explosion venting
Marchesini MA 357 continuous horizontal cartoning machine from 2002, suitable for high-speed packaging of bottles, vials, droppers, etc., in interlocking cartons with three even or alternating flaps.
Constructed entirely in balcony, it re-proposes all the features and advantages of Marchesini cartoners: carton magazine in optimal position, maximum accessibility, extremely fast changeover times, minimal maintenance.
General features:
- Cantilevered construction in maximum compliance with GMP standards
- Ergonomic position of all feeding units
- Oil-bath mechanics for low maintenance and low noise levels
- Reliability and speed
- Quick and easy format changeover, carried out entirely from the front of the machine
- Touch Screen type operator interface, allowing all machine functions to be managed and varied.
- Self-diagnosis function
- Help function to remedy any faults quickly and safely Automatic GUK prospect folding machine in operator accessible position
- Laser marking system
- Leatus barcode reader for brochures and cases.
Technical data:
Approximate net weight 2500 kg;
Installed power 7.5 kW;
Compressed air consumption at 6 bar 240 Nl/min;
Noise level < 75 dB;
Mass 2600 kg
Mechanical speed up to 400 pcs/min.
PRODUCT RANGE
Board width: approx 25 - approx 100 (mm)
Carton height: 15 mm - 85 mm
Carton length: 65 mm - 150 mm
The Seidenader lyophilisate inspection machine model LI-30 of 2004 can inspect freeze-dried product bottles with the following dimensions:
Format: Bottles 2 ml Ø 16 mm, Ferrule Ø 13 mm
Format: 3 ml bottles Ø 16 mm, ring nut Ø 13 mm
Format: Bottles 3 ml Ø 16.75 mm, Ferrule Ø 13 mm (1)
Format: Bottles 5 ml Ø 21.5 mm, Ferrule Ø 13 mm (1)
(1) The formats Bottles 3 ml Ø 16.75 mm and 5 ml Ø 21.5 mm are discontinued and are therefore not currently processed in the machine.
The mechanical speed of the machine can be set to a maximum of 300 pcs/minute, so in total the machine operates at 18,000 pcs/hour for the 2/3 ml bottle format and 15,000 pcs/hour for the 5 ml bottle format.
Via XXV Aprile, 8
21054 Fagnano Olona (VA)
Italia
Tel. +39 0331 1693557
email: inti@intisrl.it
