dosing device

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dosing device [756]

BOSCH Complete Lines BOSCH RRN3020 Bosch + HQL 3460 Bosch + MLF3002 Bosch +  TPC + Seidenader DAR150LR
Complete Lines BOSCH RRN3020 Bosch + HQL 3460 Bosch + MLF3002 Bosch + TPC + Seidenader DAR150LR
LB516
BOSCH
RRN3020 Bosch + HQL 3460 Bosch + MLF3002 Bosch + TPC + Seidenader DAR150LR
1995

Complete vial filling line consisting of:
Bosch vial washing machine RRN 3020
Bosch vial depyrogenation tunnel HQL 3460
Bosch vial filling machine model MLF 3002 complete with isolator on vial filling machine TPC
External decontamination washing machine Seidenader DAR 150-LR. There are several formats included with the line

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Aeromatic GEA Complete Lines Aeromatic GEA MP 3/2/4-K2-F1/2 SATIN
Complete Lines Aeromatic GEA MP 3/2/4-K2-F1/2 SATIN
IT519
Aeromatic GEA
MP 3/2/4-K2-F1/2 SATIN
2003

FLUID BED PROCESSOR
the plant is an all-round production machine and is suitable far:
- Fluid Bed Drying (all sorts of fluidised products)
- Spray Granulation (all kind of powdery products) via top spray procedure
- Coating of micro fine products as well as pellets via top spray procedure
- Coating of micro fine products as well as pellets via bottom spray procedure
The AEROMATIC-FIELDER Quality Pian guarantees the manufacture of the Fluid Bed Unit to the highest levels of finish/fabrication and comply with latest issue of the following standards
FDA Guidelines
European GMP's
GAMP's Guidelines revision 4
The Fluid Bed ·Unit is designed to be integrated in a wall between production and technical areas and is executed to achieve the highest levels of GMP which requires a radical separation between production equipment and peripheral mechanical and electro-pneumatic equipment. In the proposed execution only the Fluid Bed Apparatus and the membrane operator panel are in the process area.
10 bar is the recognised state of the art Fluid Bed construction and offers several advantages over conventional design
- No explosion relief duct is needed allowing for a more flexible installation,
- No environmental pollution in the event of an explosion,
- Optimum conditions for total processing containment.

Through-The-Wall-Design (TTW)
Clear separation between production area and technical area Substantial reduction in GMP space needed
No maintenance interventions needed in production area

The suggested FBD plant design allows the following processes
A) Drying in the fluid bed
A batch of fluidised wet material is put into fluidisation through an upward movement of heated air during which the whole surface of the particular product particles is in contact with the hot air. Each particle/granule is uniformly dried to low final moisture content. This is achieved as a result of an even temperature profile throughout the powder bed.
B) Agglomeration in the fluid bed
If a starting product, consisting of fine powder or core sized particles, has to be transformed/changed into a homogeneous rough sized granule it can also be done in a Fluid Bed. The appropriate liquid is sprayed onto product particles which are floating in the airflow, this produces an agglomeration of the particles. The adherence of the particles can be achieved by etching the particle surface with a spray liquid or through using or a spray liquid with a binding agent dissolved in a spray liquid. The agglomerates formed are fixed by the drying process.
C) Coating in the fluid bed (predisposition for the future use)
If individual particles of a product require coating to modify the characteristics and/or provide a protective membrane, the process is similar to that of fluidised bed spray agglomeration. The coating media is dissolved/dispersed/suspended in an appropriate carrier liquid and sprayed onto the fluidised particles. The process can be with top spray with the latter generally used for processing dense and large particles.

Fluid Bed Multi - Processor
Typical working capacity (approx.) 15 to 50 litres
Typical batch size 7.5 kg 25 kg
(Average product density 0.5 kg/I)
Max. working volume 55 litres
Granulation liquid based on Purified Water
Process inlet air heating range: 750 to 1100 m3/h at 50°C (valid far empty machine)
Process inlet air volume range: +8 to +12 °C
Process inlet dew point

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DE LAMA Autoclaves/Sterilizing Ovens/Freeze Dryers DE LAMA AUTOCLAVE DE LAMA
Autoclaves/Sterilizing Ovens/Freeze Dryers DE LAMA AUTOCLAVE DE LAMA
IT520
DE LAMA
AUTOCLAVE DE LAMA
2005

AUTOCLAVE DE LAMA
Year of construction: 2005
Chamber dimensions: H 1330 x W 920 x D 1250
Useful volume: 1530 L
Pressure 2,5 brg

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BAUSCH+STRÖBEL Liquid Filling and Closing Machines BAUSCH+STRÖBEL FFV6010
Liquid Filling and Closing Machines BAUSCH+STRÖBEL FFV6010
22C16
BAUSCH+STRÖBEL
FFV6010
2005

Filling and closing machine designed for the simultaneaous processing of 6 vials or oter small stable bottles of glass or plastic.


Working Sequence
-Feeding of the vials into the machine by a machine upstream or by manual bulk loading into a rotary table, an RPE BI-FLOW conveyor or an infeed belt with a feed screw.
- Separation of the vials by an infeed star wheel and transfer to the transport star wheel
- Dosing filling
- Closing with rubber stopper dropper insertion etc…
Discharge star wheel with transfer to the following machine or magazine loading unit .

Dosing :
The dosing station is equipped with with 6 valveless rotary piston pumps .
Thes pumps are made of two parts only and are hight-quality precision tolls which guarantee excellent dosing precision.
They are easy to remove , clean and sterilize – as are all the parts which are in contact with the product.
Depending on the product to be dispensed, the pumps may be made of stainless steel, glass or ceramics.
The CIP SIP version of the dosing units ( cleaning in place – sterilizing in place ) permits the cleaning and sterilizing of the entire dosing system without dismantling and assembly.
The central dose adjustment and the individual fine adjustment for eache pum are done by micrometer screws.
A photo cell at the infeed checks each transport pocket for the presence of a vial and controls the dosing pumps and the closing tools according to the principle “ no bottle – no filling – no closure”.

Closing:
Sorting bowls and vibratory tracks feed the stoppers, dropper inserts, etc… automatically and with low particle generation . The insertion tolls pick up the stoppers by vacuum and set them precisely in the bottle opening.
All the parts in contact with the stoppers are easy to clean ad sterilize.
They can be removed and assembled effortlessly .

Size change
Resetting the machine for a different container or closure size even under clean room conditions, is simple and quick due to :
- The exchange of complete size parts
- - finely adjustable height setting

Year of construction : 1987 3.5 kw - 50 hz - 24 v - 220/380 1780 kg

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Inova Liquid Filling and Closing Machines Inova Inova SV 122
Liquid Filling and Closing Machines Inova Inova SV 122
21C17
Inova
Inova SV 122
2005

This semi-automatic system is currently equipped with the BD-Hypak SCF system and parts in sizes 0.5 ml, 1 ml - 5 ml for nested syringes.
Two syringes are filled during each filling cycle and the filled syringes are closed with rubber stoppers.
The machine is offered complete with variable control rotary valve pumps and operates with two filling stations.
It is designed to operate at variable speed and has a maximum capacity of 4,500 syringes per hour.

Speed: 75 /min Filling volume (min): 0.2 ml Filling volume (max): 29 ml Sizes : 0.5 - 160 tray size - units - centering device 1 ml long - Tray size 160 - Units - Centering device Length: 1400 mm Width: 952 mm Height: 1877 mm Weight: 800 kg

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IMA Farmomac Closing Machines IMA Farmomac F550 / C
Closing Machines IMA Farmomac F550 / C
20C15
IMA Farmomac
F550 / C
n/a

The F550 (Serial no. 550009 ?) is an 8-head rotary seamer for automatic feeding and seaming of aluminium or flip-off capsules. The machine has been designed to work with previously filled vials and allows the application of aluminium or flip-off caps; it is also designed for in-line connection both upstream and downstream. The vials arrive at the machine via a special feeder. The vials come from the infeed belt and are closed by the rotary head. Once operations have been completed, the vials exit onto the outfeed belt or are rejected from the belt.

TECHNICAL DATA
vial dimensions
- diameter: min. 14 mm - max. 60 mm
- Height: min. 5 mm - max. 100 mm
production: 16000 vials per hour
Installed power: 3,5 KW

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kmpt Miscellaneous kmpt HZ 25/0.1
Miscellaneous kmpt HZ 25/0.1
22MF20
kmpt
HZ 25/0.1
2006

The centrifuge HZ 25/0, 1 under serial No. 60000800 (Year 2006) is suitable exclusively for the separation of the products specified on the technical data stated on the type plate.
Basket diameter 250 mm
Admissible density of the feed charge 2 000 kg/m3
Speed, max. adm. 4000 rpm
Centrifugai force C at max. adm. speed 2 235
Operating speed variable
Load, max. adm. 4,9 kg

Dimensions of complete unit (with drive motor and movable table)
Length 850 mm
Width 1090 mm
Height 1490 mm
Shipping weight (centrifuge with table, drive motor and accessories) 650 kg

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Erweka Miscellaneous Erweka Tbh 220 td
Miscellaneous Erweka Tbh 220 td
21S21
Erweka
Tbh 220 td
2020

The Erweka Tablet Hardness Tester TBH 220 measures the hardness of the tablet.
For use in pharmaceutical, chemical, cosmetic, food, dietary, medical devices
The Erweka Hardness Tester is compact for automatic measurement of hardness, diameter and thickness of tablets and similar dosage forms
Hardness measurement on the basis of two different measuring principles (constant speed, constant force) is possible.

TECHNICAL SPECIFICATIONS Dimensions (WxDxH)mm: 350x375x310 Power supply: 100VA - 230V - 0.5A - 50/60Hz Measuring principle: Load cell with wire strain gauge, constant speed (0.1 - 3.00 mm/s) or constant force (10 - 200 N/s) Throughput: 1 to 100 samples per test, preselectable, 6 to 8 samples per minute. Hardness measurement: 3 - 500 N; Hardness accuracy: ± 1 N; Hardness units: Newton, Kilopond, Strong Cobb; Thickness measurement: 0.10 - 12.00 mm; Thickness accuracy: ± 0.05 mm; Thickness units: mm or inches; Diameter measurement: 2 - 28 mm; Diameter accuracy: ± 0.05 mm; Diameter units: mm or inches. The parameters of this hardness tester are quickly set via the alphanumeric keypad and displayed on the easy-to-read LCD display. With RS232C and printer interfaces for data logging.

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SARONG Tube Filler Machines/Suppositories fillers SARONG SAAS 15AP
Tube Filler Machines/Suppositories fillers SARONG SAAS 15AP
15S23
SARONG
SAAS 15AP
1990

FEATURES
Output:
up to 30,000 suppositories per hour (aluminium version)
up to 26,000 suppositories per hour (plastic version)
Hopper capacity: 80 litres
Hopper heating: by means of electrical resistance and water bath Material reels diameter:
standard 490 mm - optional 550 mm
Maximum width of film: 65 mm
Packaging materials:
Aluminium:
duplex (ALU/PE - ALU/thermowelding coating) triptex (PP/ALU/PE) - PP/ALU/thermowelding coating) Thickness o! aluminium foil: 70 to 100 microns

Plastic:
PVC, PVCIPE, PVC/ PVDCIPE and other thermowelding materials.
Thickness of plastic film: 100 to 150 microns Thermoregulating board lor temperatures contro! in the panel Cooling time: two stages 8 minutes - tour stages 16 minutes Minimum cooling temperature: 3°C
Suppository cooling unit power:
two stages: 4400 frig./hour with temperature at 3°C
tour stages: (with one stage heated or at room temperature) 6600 frig./hour - tour stages: 8800 frig./hour

Air consumption:
aluminium version max 80 NUmin. plastic version max. 120 NL/min. at working pressure of 5 kg/sq.cm.
Water consumption: 6 to 8 1/mìn.
optional: water closed circuit with central pumping station of 6000 frig./hr. (two-stage version) and of 11000 frig./hr. (tour-stage version)
Nominal power:
Aluminium version: 2 cooling stages 9 kW - 4 cooling stages 12 kW Plastic version: 2 stages 1 o kW - 4 stages 13 kW
Auxiliary input: 24 Vac - 24 Vdc .
Standard input voltage: 220-380 V, 3-phase, 50 Hz
other voltage ratings available on request

Length dimension inclusive of heat seat station distanced from batching
station 800 mm approx.
Height of strip from floor at runout: 960 mm
Weight: SMS/15-AP - two stage - 2300 kg
SMS/15-AP - four stage - 2800 kg

Measures: height 2240 mm x length 6970 mm x width 2040 mm

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MAR Aseptic Filling and Closing Machines MAR MC-9TS/1A
Aseptic Filling and Closing Machines MAR MC-9TS/1A
22F33 - 22F85
MAR
MC-9TS/1A
1999

Filling machine for nasal sprays and eye drops
Special equipment: Two isokinetic probes for particle control including vacuum pump
Manufacturer: MAR
Model: MC-9TS/1A
Year of construction: 1999
Weight: 1600 kg

Here are the details:
Possible formats:
20 ml nasal spay Snap on
10 ml eye drops screw closure
20ml flanging
30ml flanging

Speed
Nasal spray approx. 45 units/min.
Eye drops approx. 32 units/min. 20-30 flanging approx. 35 pcs/min
Max. speed 50 units/min. /(manufacturer's specification)

Connections:
Current: 4 kw/ 380 V 50 Hz
Air pressure: min. 5 bar

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PAGO Labelling Machines PAGO 188
Labelling Machines PAGO 188
22MF55
PAGO
188
1997

Pago ticket labelling system 188
No 0618845 BJ 1997

Technical data:
Machine LxWxH 2200x1300x1400mm
Switch cabinet integrated in base frame
weight approx. 300kg
Production capacity: approx. 30-60 st/min

Power supply:
Electric:
Voltage 400V 50 HZ 3
Rated current 1,2 A
Pneumatic:
Pressure 6 bar

Label rolls
Core diameter 76 mm
Maz. Outer diameter 280 mm

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Neri Marchesini Complete Lines Neri Marchesini complete line for bottle filling and packaging
Complete Lines Neri Marchesini complete line for bottle filling and packaging
22F51
Neri Marchesini
complete line for bottle filling and packaging
1997

complete line for bottle filling and packaging consisting of :

-NERI Turn table before Filling machine, Μodel: S, Type: I6, SN: MTFA 01201 with integrated bottles air cleaning unit .
-ΜΑRCHESINI Glass Bottles Filling machine- Type: ΜL646- SN: 696000095, Manufacturing Year: 1996, (bottles: 20 ml, 50 ml, 100 ml)
-Turn Table before Cartoner machine, Model: DMCS, SN: 696000095
-MARCHESINI Cartoner – Type : MA155- SN:396000170, Manufacturing Year: 1997.

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Neri Marchesini Washing Machines for Ampoules and Vials/Blowing Table for Bottles Neri Marchesini NERI Turn Table before filling machine  S6
Washing Machines for Ampoules and Vials/Blowing Table for Bottles Neri Marchesini NERI Turn Table before filling machine S6
22F52
Neri Marchesini
NERI Turn Table before filling machine S6
1997

Automatic bottle and vial blower linear type, complying with cGMP regulations, suitable for handling bottle range, complete with compressed air feed system complying with FDA standards.
Main features:
Basic machine with plate paneling in AISI304 stainless steel satin finish and with internal components which come in contact with the blowing air in AISI316L. Blowing air contact pipe work and components mirror lapped, with tri-clamp fittings. Internal plunger-needle blowing system. Intermittent vials / bottle blowing system. Accessibility to the internal working of the machine for cleaning operations.Bottles infeed in line to a tabletop conveyor belt, with provision to connection with the upstream machine and directly connected to the vertical blowing wheel.
Vertical air blowing wheel, complete with 16 pockets and 16 blowing needles. Circuit for compressed air blowing with sanitary piping, pressure reducer, PALL filter housing, membrane electro valve, spraying needles and suction manifold. Safety torque limiter on the blowing wheel.Underlying particles collection tank with 40 mm diameter suction orificeIndependent drive for conveyor belt and pocketed wheel with working speed control.Bottles out feed in line to a tabletop conveyor belt, with provision to connection with the downstream machine. Backup sensor on bottle out feed.

Voltage : 380 v - 50 hz Weight: 390 kg Model S6 Air 6 Bar

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MARCHESINI GROUP Liquid Filling and Closing Machines MARCHESINI GROUP ML 646
Liquid Filling and Closing Machines MARCHESINI GROUP ML 646
22F53
MARCHESINI GROUP
ML 646
1996

Automatic intermittent motion machine, suitable to fill bottles with liquid.
Nozzle movement performing fractional filling of the total volume.
One or two intermittent motion Plugging/Capping groups.
The ML640 model is specific for capping operation only.
Main Features:
Stainless steel covered frame.
Separation between the bottle transport and mechanical area.
Machine main drive unit with electronic speed variation.
FLEX-LINK tabletop conveyor for bottle infeed and discharge with stainless steel adjustable guides.
Independent servo driven units with speed adjustment from Display.
Carousel with 15 pockets to transport and place the bottles under the filling/closing heads.

DOSING RANGE With stainless steel syringes: 1 - 500 ml With ceramic syringes: 1 - 300 ml CONTAINER SIZE Ø of round bottle: 18 - 90 mm Width x Width, square bottle: 20 - 80 mm Long side, rectangular bottle: 20 - 85 mm Short side, rectangular bottle: 20 - 60 mm Tot. height, without closure: 35 - 180 mm OUTPUT Production speed: Up to 75 Cycles/Min.

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Ponzini Water Treatment/Distillation Units/Reverse Osmosis/Pure Steam Generators Ponzini FD 12
Water Treatment/Distillation Units/Reverse Osmosis/Pure Steam Generators Ponzini FD 12
22F102
Ponzini
FD 12
1987

Ponzini thermocompression distillation plant for distilled water production
Model BD/pr-E.V. (AT-AV)
Hourly capacity 330 litres
Serial number 2754

Current three-phase 380 volts 50 Hz
Current single-phase 24 volts 50 Hz
Electrical power 59 Kw
Steam compressor type SCL-710
Distilled water recycling pump type Prolac S18 MB 1.1 CIE

Energy consumption during steady running to produce distilled water a:

with electric heating 25/30C. 85/90C.

auxiliary heating 2 KWH 20 KWH
motive power 4.5 KWH 4.5 KWH

with steam heating

auxiliary heating 4 KWH 34 KWH
motive power 4.5 KWH 4.5KWH

consumption for system preheating and steam compressor with system
electric power consumption 20 KWH steam heating 34 KGH

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CONTACTS

INTIMAC s.r.l.

Via XXV Aprile, 8

21054 Fagnano Olona (VA)

Italia

Tel. +39 0331 1693557

email: inti@intisrl.it

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