+39 0331 1693557
inti@intisrl.it
Download of all our available used machinery
The FOA air-steam steriliser from 2003 is suitable for:
- Sterilisation of parenteral solutions, liquids in closed non-deformable containers (e.g. glass tubes) and liquids in closed deformable containers (e.g. plastic bags or bottles).
- Terminal sterilisation of pre-filled syringes.
The machine is designed to operate with the new RTWS3 temperature sensors, which, especially in the large automatic loading models, offer unparalleled ease of use and optimal process control:
It is equipped with fully automatic discharge/loading conveyors for maximum
productivity with virtually zero maintenance inside the sterilisation chamber.
Where the product is subject to separation or to accelerate the thermal transition phases, the entire load can be rotated throughout the process.
Steam-air FOA process:
Magnetically driven fans force a high rate of fluid circulation within the chamber. Internal sanitary hollow plates add additional heating/cooling capacity, minimising the creation of condensation.
Steam and air are injected according to control algorithms to finely control the process.
This system is the usual choice when terminally sterilised products need to be dry-discharged.
Superheated water FOW process:
Water is continuously circulated through the system and sprayed onto the load. Fine control of heating and sterilisation is achieved by superheating the water with modulated steam.
Cooling of the load is achieved by subsequent cooling of the circulated water.
Back pressure control is in accordance with the steam-air mixing process. The process is efficient and faster than the FOA process.
It is also an ideal process for processing at <105 °C. Wet loads can be overcome by using an automated drying extension with the installation of specific drying solutions downstream of the sterilisation chamber.
Maximum permissible pressure ps (bar) inner chamber -1/3 outer chamber 2.5
Maximum permissible temperature ts(°C) inner chamber 143.6 outer chamber 138.9
Volume (V) inner chamber 13.080 l outer chamber 48x4
Test pressure pt (bar) inner chamber 4,6 outer chamber 5,3
Uhlmann blister machine UPS4 year of manufacture 1999
min.-max. forming width 62 - 226 mm
cycles: 15-50 cycles/min
depth: pvc 12 mm alu 10 mm
blister format: min. 60 mm max. 140×39 mm
punching area: length 226 mm, width 284 mm
forming film width: min. 100 mm max. 298 mm
covering foil width: min. 100 max. 298
tooling: pvc/alu - 6 blisters of 39×94 mm
alu-alu - 7 blisters of 38×86 mm tablet check :
The FOA air-steam steriliser from 2003 is suitable for:
- Sterilisation of parenteral solutions, liquids in closed non-deformable containers (e.g. glass tubes) and liquids in closed deformable containers (e.g. plastic bags or bottles).
- Terminal sterilisation of pre-filled syringes.
The machine is designed to operate with the new RTWS3 temperature sensors, which, especially in the large automatic loading models, offer unparalleled ease of use and optimal process control:
It is equipped with fully automatic discharge/loading conveyors for maximum
productivity with virtually zero maintenance inside the sterilisation chamber.
Where the product is subject to separation or to accelerate the thermal transition phases, the entire load can be rotated throughout the process.
Steam-air FOA process:
Magnetically driven fans force a high rate of fluid circulation within the chamber. Internal sanitary hollow plates add additional heating/cooling capacity, minimising the creation of condensation.
Steam and air are injected according to control algorithms to finely control the process.
This system is the usual choice when terminally sterilised products need to be dry-discharged.
Superheated water FOW process:
Water is continuously circulated through the system and sprayed onto the load. Fine control of heating and sterilisation is achieved by superheating the water with modulated steam.
Cooling of the load is achieved by subsequent cooling of the circulated water.
Back pressure control is in accordance with the steam-air mixing process. The process is efficient and faster than the FOA process.
It is also an ideal process for processing at <105 °C. Wet loads can be overcome by using an automated drying extension with the installation of specific drying solutions downstream of the sterilisation chamber.
Maximum permissible pressure ps (bar) inner chamber -1/3 outer chamber 2.5
Maximum permissible temperature ts(°C) inner chamber 143.6 outer chamber 138.9
Volume (V) inner chamber 13.080 l outer chamber 48x4
Test pressure pt (bar) inner chamber 4,6 outer chamber 5,3
The F400S is a closing filling machine designed to perform in-line filling and capping operations for aseptic glass bottles. The machine consists of the following units: bottle infeed conveyor, screw conveyor unit, filling carousel, capping carousel, bottle outfeed and rejection carousel, syringe unit, chasing nozzle head, transfer carousel, vibrating cap sorter, bottle rejection conveyor, bottle outfeed carousel, transfer carousel, post-fill gassing tunnel, laminar flow, sampling belt, pre-corking gassing tunnel, bottle stop piston.
SECTOR OF USE:
Pharmaceutical, chemical, cosmetic, food, dietary, medical devices, manufacturing.
PECULIARITY:
The bottles are brought to the first conveyor star by the incoming conveyor belt, passing by an auger that has the function of putting the bottles in phase with the carrousel itself, then they are passed to the second transfer star and given to the filling carrousel. The full bottle is then passed to the capping carrousel. At the end of the operation, the finished product is passed from the exit carrousel to the exit or rejection belt.
The various operational phases are briefly divided into:
-conveyance of incoming bottles,
-filling bottles,
-tapping bottles,
-flowing bottles,
-discarding non-compliant bottles or sampling.
Last format processed: 100 ml glass bottle, cap diameter 30.9 mm, flip-off ring diameter 37.0 mm.
The filling machine is complete with rotary table, LAF filtration hood system, 100 ml format and modular transmitter brand Mettler Toledo model M700 which with ISM technology allows perfect integration of sensor diagnostics.
Year of construction: 2006
TECHNICAL SPECIFICATIONS Length mm 5000 Width mm 2300 Height mm 2050 Weight Kg 3500 Power kW 17 Frequency Hz 50 Voltage Volt 400 Max. output Bottles/min 400
The Getinge Autoclave is designed for the sterilization of porous or laboratory materials, which are capable of withstanding seam at high temperatures in excel of 100°C.
The Autoclave is supplied with the following process cycles and test facilities:
1. Vacuum Cycle
2. Leak Test
3. WarmUp and ALRT combined
Mechanical Enclosure
Fascia Panels
the sterilizer is a recessed installation with fascia panels to the loading side only.
Material: Stainless steel 1.4301 (AISI 304).
Front surface texture: Tetra polished Ra< 1,2 micrometer
Thickness 1.0 mm.
Loading area / Plantroom area Barrier
There is no requirement for a barrier.
Pressure Vessel
Loading Height: 300 mm from floor to the chamber bottom.
Chamber
Internal Dimensions
Useable width 700 mm
Useable height 1450 mm
Useable depth 1350 mm
Construction:
Cross section: Rectangular
Material: AISI 316L acid proof stainless steel
Design pressure: 3 bar (g) & full vacuum
Design temperature: 143 °C
Welds: Robotic or semi-automatic whenever possible
Internal Chamber and Ports Finish
internal surface ground and polished to a high lustre
Internal Ra value 0.6 microns
1 Door
Design: Fully automatic, horizontal sliding
Opening and closing: Automatic button controlled
Door operation: Pneumatic motor
Door safety: Stops and reverses if obstructed. Door close isolation keyswitch to prevent door closing if access to chamber is required.
Internal door surface: AISI 316L stainless steel
Door pins: AISI 316 stainless steel
Media (Utility) Requirements
Please refer to the installation drawing for details of sizes & consumptions.
Requirements:
Steam
Compressed Air Supply
Potable Water Supply
Cooled Water Supply
Condense
The FOB benchtop autoclave series is suitable for many applications, making it a perfect choice to meet the needs of a modern laboratory, thanks to the combination of technology and construction know-how, and can be used in very different environments:
- Public and private microbiological laboratories.
- Universities and colleges.
- Research institutes, biotech and life science laboratories.
- Diagnostic laboratories.
- Veterinary and environmental laboratories.
- Laboratories for stress tests on materials.
- Quality laboratories in pharmaceutical, food, cosmetics companies etc.
The FOB is suitable for handling different types of cargo, including laboratory waste with a pathogenic risk, as well as porous solids, bagged instruments and liquids/contrast media in open or hermetically sealed containers.
The bench-top autoclaves of the FOB series are used in very specialised fields requiring validated and reproducible processes, but remain very flexible due to the great variety of options provided by the modularity of our autoclaves.
FOB3-TS: 90 litre, single folding door;
The door opening and closing system is unique due to the patented hermetic closure system with pneumatic gasket, which guarantees perfect watertightness, maximum reliability and safety for the user. In addition, the autoclaves in this series are equipped with a safety system, which prevents the doors from opening and provides increased safety for the user.
The chambers, pneumatic valves and hydraulic components are made of 316L stainless steel with an electropolished finish. The FOB autoclave series has been developed to provide ample and convenient access to the technical area for routine and extraordinary maintenance.
Air steam 153 L max allow temp. 152 ° max allow pressure 4 barg press test 6.6 barg
he 2003 IMA MS500BP automatic shrinkwrapper is equipped with a manual self-holding stop. The presence of foreign body under the welding device or the infeed unit overloaded causes the automatic emergency stopping of the machine due to the action of safety microswitch. The welder is supplied with teflon coating and spring support. The main motorization consists of a self-braking motor complete with expansible pulley for speed adjustment that has a fixed diameter pulley with fiction clutch, one chain for motion transmission from the reduction unit to the camshaft. By varying the diameter of the expansible pulley the machine speed changes. The input of the bundle in the welding area is made by means of the plate towed by a chain operated by a self-braking geared motor.
– Infeed belt conveyor for bottles
– Induction sealer
– Staging and intermittent feed for different bottle sizes
– Very compact design machine
– Equipped with shrink tunnel with internal circulating fan and discharge cooling fan
TECHNICAL DATA Frequency Hz 50 Voltage Volt 380 Production up to bundles/min 30 PE Film Width mm: mm 50-500 Film roll Max diameter mm 300 Tunnel opening mm 230 x 560 Case Height 12-100 mm Case Width 15-330 mm Case Length 50-300 mm Bundle Height 30-200 mm Bundle Width 15-300 mm Bundle Length 60-330 mm
The bottle closing machine in modified atmosphere and vacuum, has been designed and built according to the most modern and advanced technologies. All the solutions adopted are the result of research and design aimed at building safe, reliable machines capable of guaranteeing high quality and production standards.
The machine has been built with high quality components to guarantee low maintenance and a long working life. The piping, fittings, valves, materials and installed instrumentation comply with F.D.A. directives.
All machine parts, smooth surfaces, rounded corners have been specially designed to facilitate cleaning and sanitising.
SECTOR OF USE:
Pharmaceutical, chemical, cosmetic, food, dietary, medical devices, manufacturing.
PECULIARITY:
The bottle capping process is divided into the following stages:
1. Bottle infeed: The containers coming from the line arrive at the machine where an auger sets them up at the machine's pitch. The screw feeder leads the bottles into the infeed starwells where, after a rotation of about 180°, they are deposited on the carousel plates.
2. Capping in a modified atmosphere: The infeed star deposits the bottles onto the carousel platters, which move the bottle towards the capping head; the bottle capping procedure is divided into the following stages: Bottle Lifting, Bottle Uncapping, Bottle Vacuum, Bottle Nitrogen and Cap, Bottle Vacuum, Bottle Capping, Bottle Descent and Release.
3. Bottle unloading: The exit star receives the bottles from the capping carousel and deposits them after a rotation of about 180° on the exit belt, close to the ejector.
4. Bottle rejection: The rejection system is implemented by means of a system called Soft Push, characterised by the presence of a pad covered with absorbent material and driven by a pneumatic cylinder. Upon receiving the rejection signal from the machine's control logic, the pad comes out, hits the containers with capping imperfections and moves them to an independent rejection accumulation. Conversely, suitable bottles will be free to flow to the next process.
The production speed can be varied by acting on appropriate parameters settable from the control panel. The maximum speed attainable is 9,000 bottles per hour with 100ml bottles.
Year of construction: 2006
Length mm 4550 Width mm 2310 Net weight Kg 5000 Frequency Hz 50 Voltage Volt 380 TECHNICAL PRODUCTION CHARACTERISTICS Production 9000 Bottles / h (100 ml) Size of treated bottles 50 / 100 ml Treated bottles material: glass Steam consumption 300 Kg / hour Water consumption 18 lt / min
Cartoning machine VOLPAK Model PAK 1300
Year : 1995
Technical data :
380 v - 2.2 A - 50 Hz
Machine dimensions
Length: 340 cm
Width: 160 cm
Height: 160 cm
Tablet press KORSCH PH 250 PHK2.03232 from year 1992 with manuals
Die and punch type: Euro B
Specific Details
Number of tablets:161280 /h
Number of press stations:30
Maximum Pressure:2080 Kn
Maximum tablet diameter :13 mm
Maximum tablet thickness:8,5
Length:ca 830 mm
Width: ca 980 mm
Height: 1750 mm
Weight: 1650 kg
PROCESS CONCEPT
The ESS/CCA dryer uses control systems, influenced by specific drying programs, which eliminates problems related to the interaction of solid particles with a gas that are typified by:
- The formation of air channels within the granulated mass
- The lack of uniformity in the drying process
- Localized overheating of the granulation in some parts of the bed attrition of the granulation as it dries
DRYING PROGRAM
ESSICCA is equipped with software that allows diferent drying programs to be selected depending on the nature of the material being dried.
Examples Of possible drying programs include:
- Constant air flow and product temperature
- Using progressive air flow that changes with time
- Using immediate fluidization
- Using controlled fluidization determined by temperature gradient
ESSICCA can measure 7 (seven) parameters at the same time during the process:
- In/ct air temperatura: Ti
- Temperature ofthe air in contact with granulated material: Tp
- Exhaust air temperature: Te
- Pressure within the expansion chamber: Pce
- Pressure in the plenum.. Pp
- Pressure at the exhaust.. Pe
- Air flow: Q
Measurements are constantly processed by means of a PLC which provides information based on the selected drying program.
Rommelag Type 305M was operational and has been used to fill sterile pharmaceutical product into unit dose vials
- 2, 2.5 & 4ml Unit Dose Vials at 11000 UDV’s per hour.
- Steam In Place qualification and media runs were performed annually.
Machine Specifications: Reference Data:
- Machine Type: 305M
- Built: 1993
- Machine No: 3523-145/579,92
Dimensions & Weight:
- Weight: approx. 7000kgs
- Length: approx. 3150mm
- Width: approx. 2825mm
- Height: approx. 2800mm
Emissions:
- Noise: 77 dB(A)
Services Specifications: Electrical:
- Enclosure type: IP54
- Supply Voltage: 3 x 400 V+N, PE
- Frequency: 50 HZ
- Current: 120 A
- Control Voltage: 24 V DC
- Main Fuse: 125 A
- Rated Power Consumption: 80 kVA
Pneumatic:
- Air Pressure: 8 bar
- Max. Consumption: 350 l/min
Hydraulic:
- Pressure: max. 160 bar
- Hydraulic motor: 11 kW
Miscellaneous Machine Data:
- Extruder Ø: 45 mm (9 D)
- Extruder motor: 32kW
- Plastic granulate used: LDPE
- Plasticizing capacity for plastic granulate: 65 kg/h
- Steam: 2.5 bar; purity <1 μm
• Consumption for preparation: 40 kg/h
• Consumption for production: 15 kg/h
- Cooling water: 12 ºC, 4 bar; <55 μm / 12 ºdH
• Consumption: 2 m3/h
included
- Rommelag Type 305M BFS Machine.
- Moulds will be supplied with the machine, but without any product coding.
- Machine conveyors
- Chr. Stougaard PGT 34 Polyloader.
- Jenco HD50T Dryer.
- Hydraulik 32-1,31-00-3 Hydraulic Pack.
- Vacuum Pump Assembly.
- Operational and Maintenance documentation
Rommelag Type 3012 BFS was last operational and used to fill sterile pharmaceutical product into unit dose vials
- 1, 2, & 4ml Unit Dose Vials at 3300 UDV’s per hour.
Additionally, the machine has the tooling available to produce 2.5, 5 & 10ml ampoules
Included:
- Moulds will be supplied with the machine
-Machine conveyors
-NEU Engineering Polyloader.
-Virgin Gran Vacuum Pump.
-Hydraulik 321-1.31-00-3 Hydraulic Pack.
-Vacuum Pump Assembly.
-Operational and Maintenance documentation.
Dimensions & Weight:
-Weight: approx. 3500kgs -Length: approx. 2130mm -Width: approx.
1370mm -Height: approx. 2700mm
Emissions:
-Noise: 78 dB(A)
Services Specifications:
Electrical:
-Enclosure type: IP54
-Supply Voltage: 400V 3 Phase V+N, PE -Frequency: 50 HZ
-Current: 65A
-Control Voltage: 24V DC
-Main Fuse: 80A
-Rated Power Consumption: 30 kWh
Pneumatic:
-Air Pressure: 8 bar
-Max. Consumption: 250 l/min
Hydraulic:
-Pressure: max. 100 bar
-Hydraulic motor: 7.5 kW
Miscellaneous Machine Data:
-Extruder Ø: 35 mm (24 D)
-Extruder motor: 27kW
-Plastic granulate used: LDPE
-Plasticizing capacity for plastic granulate: 35 kg/h
Ambient Conditions:
-Temperature (machine):
• Storage temperature: 15-30 °C
• Operating temperature: 15-30 °C
-Air moisture: 40-80%
Via XXV Aprile, 8
21054 Fagnano Olona (VA)
Italia
Tel. +39 0331 1693557
email: inti@intisrl.it
